Successful pregnancies but a higher risk of preterm births in patients with systemic sclerosis: An Italian multicenter study

Mara Taraborelli, Véronique Ramoni, Antonio Brucato, Paolo Airò, Gianluigi Bajocchi, Francesca Bellisai, Domenico Biasi, Jelena Blagojevic, Valentina Canti, Roberto Caporali, Paola Caramaschi, Ilaria Chiarolanza, Veronica Codullo, Franco Cozzi, Giovanna Cuomo, Maurizio Cutolo, Maria De Santis, Salvatore De Vita, Emma Di Poi, Andrea DoriaPaola Faggioli, Maria Favaro, Gianfranco Ferraccioli, Clodoveo Ferri, Rosario Foti, Alessandro Gerosa, Maria Gerosa, Sarah Giacuzzo, Leopoldo Giani, Dilia Giuggioli, Massimo Imazio, Michele Iudici, Annamaria Iuliano, Roberto Leonardi, Massimiliano Limonta, Andrea Lojacono, Chiara Lubatti, Marco Matucci-Cerinic, Antonino Mazzone, Marianna Meroni, Pier Luigi Meroni, Marta Mosca, Mario Motta, Marina Muscarà, Simona Nava, Melissa Padovan, Giorgio Pagani, Giuseppe Paolazzi, Susanna Peccatori, Viviana Ravagnani, Valeria Riccieri, Edoardo Rosato, Patrizia Rovere-Querini, Felice Salsano, Alessandro Santaniello, Raffaella Scorza, Chiara Tani, Gabriele Valentini, Guido Valesini, Massimo Vanoli, Barbara Vigone, Silvana Zeni, Angela Tincani

Research output: Contribution to journalArticlepeer-review

Abstract

Objective To assess fetal and maternal outcomes in women with systemic sclerosis (SSc). Methods Prospectively collected data on 99 women with SSc from 25 Italian centers were analyzed retrospectively. Women with SSc were observed during 109 pregnancies (from 2000 to 2011), and outcomes were compared to those in the general obstetric population (total of 3,939 deliveries). The maternal age at conception was a mean ± SD 31.8 ± 5.3 years, and the median disease duration at conception was 60 months (range 2-193 months). Results SSc patients, compared to the general obstetric population, had a significantly increased frequency of preterm deliveries (25% versus 12%) and severe preterm deliveries (

Original languageEnglish
Pages (from-to)1970-1977
Number of pages8
JournalArthritis and Rheumatism
Volume64
Issue number6
DOIs
Publication statusPublished - Jun 2012

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Rheumatology
  • Pharmacology (medical)

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