Successful pregnancy following gonadotropin therapy in a young female with juvenile idiopathic hemochromatosis and secondary hypogonadotropic hypogonadism

G. Farina, C. Pedrotti, P. Cerani, A. Rovati, E. Strada, G. Bergamaschi, L. Montanari

Research output: Contribution to journalArticle

Abstract

Heart failure and hypogonadotropic hypogonadism are the most frequent clinical problems encountered in patients with juvenile idiopathic hemochromatosis (JIH). In this context, amenorrhea is one of the first symptoms in female patients, and hormone therapy must be added to phlebotomy to restore menstrual cycles. Here we report the case of a woman in childbearing age with hypogonadotropic hypogonadism due to JIH. Following therapy with gonadotropinic hormones the patient had a twin pregnancy with term delivery. The newborns presented a normal iron status. This confirms that early diagnosis and treatment of JIH are important to prevent irreversible organ damage and shows that the female reproductive function can be preserved in adequately treated patients.

Original languageEnglish
Pages (from-to)335-337
Number of pages3
JournalHaematologica
Volume80
Issue number4
Publication statusPublished - 1995

Fingerprint

Hypogonadism
Gonadotropins
Pregnancy
Hormones
Twin Pregnancy
Phlebotomy
Amenorrhea
Therapeutics
Menstrual Cycle
Early Diagnosis
Iron
Heart Failure
Newborn Infant
Type 2 Hemochromatosis

Keywords

  • hemochromatosis
  • hypogonadism

ASJC Scopus subject areas

  • Hematology

Cite this

Successful pregnancy following gonadotropin therapy in a young female with juvenile idiopathic hemochromatosis and secondary hypogonadotropic hypogonadism. / Farina, G.; Pedrotti, C.; Cerani, P.; Rovati, A.; Strada, E.; Bergamaschi, G.; Montanari, L.

In: Haematologica, Vol. 80, No. 4, 1995, p. 335-337.

Research output: Contribution to journalArticle

@article{935f0c3846dd425581bfeb959b181cfc,
title = "Successful pregnancy following gonadotropin therapy in a young female with juvenile idiopathic hemochromatosis and secondary hypogonadotropic hypogonadism",
abstract = "Heart failure and hypogonadotropic hypogonadism are the most frequent clinical problems encountered in patients with juvenile idiopathic hemochromatosis (JIH). In this context, amenorrhea is one of the first symptoms in female patients, and hormone therapy must be added to phlebotomy to restore menstrual cycles. Here we report the case of a woman in childbearing age with hypogonadotropic hypogonadism due to JIH. Following therapy with gonadotropinic hormones the patient had a twin pregnancy with term delivery. The newborns presented a normal iron status. This confirms that early diagnosis and treatment of JIH are important to prevent irreversible organ damage and shows that the female reproductive function can be preserved in adequately treated patients.",
keywords = "hemochromatosis, hypogonadism",
author = "G. Farina and C. Pedrotti and P. Cerani and A. Rovati and E. Strada and G. Bergamaschi and L. Montanari",
year = "1995",
language = "English",
volume = "80",
pages = "335--337",
journal = "Haematologica",
issn = "0390-6078",
publisher = "NLM (Medline)",
number = "4",

}

TY - JOUR

T1 - Successful pregnancy following gonadotropin therapy in a young female with juvenile idiopathic hemochromatosis and secondary hypogonadotropic hypogonadism

AU - Farina, G.

AU - Pedrotti, C.

AU - Cerani, P.

AU - Rovati, A.

AU - Strada, E.

AU - Bergamaschi, G.

AU - Montanari, L.

PY - 1995

Y1 - 1995

N2 - Heart failure and hypogonadotropic hypogonadism are the most frequent clinical problems encountered in patients with juvenile idiopathic hemochromatosis (JIH). In this context, amenorrhea is one of the first symptoms in female patients, and hormone therapy must be added to phlebotomy to restore menstrual cycles. Here we report the case of a woman in childbearing age with hypogonadotropic hypogonadism due to JIH. Following therapy with gonadotropinic hormones the patient had a twin pregnancy with term delivery. The newborns presented a normal iron status. This confirms that early diagnosis and treatment of JIH are important to prevent irreversible organ damage and shows that the female reproductive function can be preserved in adequately treated patients.

AB - Heart failure and hypogonadotropic hypogonadism are the most frequent clinical problems encountered in patients with juvenile idiopathic hemochromatosis (JIH). In this context, amenorrhea is one of the first symptoms in female patients, and hormone therapy must be added to phlebotomy to restore menstrual cycles. Here we report the case of a woman in childbearing age with hypogonadotropic hypogonadism due to JIH. Following therapy with gonadotropinic hormones the patient had a twin pregnancy with term delivery. The newborns presented a normal iron status. This confirms that early diagnosis and treatment of JIH are important to prevent irreversible organ damage and shows that the female reproductive function can be preserved in adequately treated patients.

KW - hemochromatosis

KW - hypogonadism

UR - http://www.scopus.com/inward/record.url?scp=0029092104&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029092104&partnerID=8YFLogxK

M3 - Article

C2 - 7590503

AN - SCOPUS:0029092104

VL - 80

SP - 335

EP - 337

JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 4

ER -