Successful selective arterial embolizations for bone metastases in renal cell carcinoma integrated with systemic therapies: A case report

L Gatto, Giancarlo Facchini, M Saponara, M. Nannini, Giuseppe Rossi, Valerio Scioscio, Guido Biasco, Maria A. Pantaleo

Research output: Contribution to journalArticlepeer-review

Abstract

Herein is described the case of a 64-year-old patient affected by metastatic clear-cell carcinoma, with exclusive bone disease, subjected after the initial cytoreductive nephrectomy to 3 successive lines of medical treatment (sunitinib, everolimus, and sorafenib) and multiple locoregional treatments (spinal surgery, radiation therapy, and selective arterial embolization), resulting in a surprisingly long survival of over 75 months. In the era of target therapy, integration strategies, including additional locoregional treatment to medical therapy, are essential to optimize the clinical benefit, to maximize treatment duration overcoming focal progressive disease, and to improve the quality of life. In this context, we would highlight that selective transcatheter embolization of bone metastases from renal cell carcinoma should be considered as an effective and safe option in the palliative setting for patients with bone metastasis, especially for pain relief.
Original languageEnglish
Pages (from-to)775-779
Number of pages5
JournalRadiology Case Reports
Volume12
Issue number4
DOIs
Publication statusPublished - Aug 16 2017

Keywords

  • Renal cell carcinoma
  • Arterial embolization
  • Bone metastases
  • Locoregional therapy
  • Integration strategy

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