Successful surgical salvage of pancreas allograft

Elena Orsenigo, Marco Cristallo, Carlo Socci, Renato Castoldi, Paolo Fiorina, Laura Invernizzi, Rossana Caldara, Antonio Secchi, Valerio Di Carlo

Research output: Contribution to journalArticle

Abstract

Background. Early and late complications related to the pancreas after simultaneous kidney-pancreas transplantation (SKPT) frequently result in graft loss. The authors describe a surgical rescue technique that allows salvage of the pancreatic graft when surgical complications appear after the transplant. Methods. Of 158 patients who underwent SKPT, 7 were identified with posttransplant complications that required surgical salvage of the pancreas allograft. The surgical salvage technique consisted of the following: pancreatoduodenectomy with conversion from whole-pancreas transplant with bladder or enteric diversion to segmental graft with duct injection (three cases) and conversion from whole-pancreas transplant with duct injection (four cases). Results. Five of seven pancreas allografts are still functioning, with a mean follow-up of 28 months (range, 6-42 months). Conclusion. The described surgical treatment may be useful for surgical salvage of the pancreatic allograft, without major impairment of endocrine function.

Original languageEnglish
Pages (from-to)233-236
Number of pages4
JournalTransplantation
Volume75
Issue number2
DOIs
Publication statusPublished - Jan 27 2003

ASJC Scopus subject areas

  • Transplantation
  • Immunology

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    Orsenigo, E., Cristallo, M., Socci, C., Castoldi, R., Fiorina, P., Invernizzi, L., Caldara, R., Secchi, A., & Di Carlo, V. (2003). Successful surgical salvage of pancreas allograft. Transplantation, 75(2), 233-236. https://doi.org/10.1097/01.TP.0000041784.27763.A9