Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance

C. Sarrecchia; V. Svicher; A. Volpi; R. Salpini; L. Ceccarelli; P. Sordillo; A. Bertoli; C. F. Perno; M. Andreoni

doi:10.1007/s15010-011-0127-3

Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance

C. Sarrecchia, V. Svicher, A. Volpi, R. Salpini, L. Ceccarelli, P. Sordillo, A. Bertoli, C. F. Perno, M. Andreoni

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log ₁₀ IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success (serum HBV DNA

Original language	English
Pages (from-to)	367-370
Number of pages	4
Journal	Infection
Volume	39
Issue number	4
DOIs	https://doi.org/10.1007/s15010-011-0127-3
Publication status	Published - Aug 2011

Keywords

Drug resistance
Entecavir
Hepatitis B
Immunocompromised
Therapy

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1007/s15010-011-0127-3

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Sarrecchia, C., Svicher, V., Volpi, A., Salpini, R., Ceccarelli, L., Sordillo, P., Bertoli, A., Perno, C. F., & Andreoni, M. (2011). Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. Infection, 39(4), 367-370. https://doi.org/10.1007/s15010-011-0127-3

Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. / Sarrecchia, C.; Svicher, V.; Volpi, A.; Salpini, R.; Ceccarelli, L.; Sordillo, P.; Bertoli, A.; Perno, C. F.; Andreoni, M.

In: Infection, Vol. 39, No. 4, 08.2011, p. 367-370.

Research output: Contribution to journal › Article › peer-review

Sarrecchia, C, Svicher, V, Volpi, A, Salpini, R, Ceccarelli, L, Sordillo, P, Bertoli, A, Perno, CF & Andreoni, M 2011, 'Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance', Infection, vol. 39, no. 4, pp. 367-370. https://doi.org/10.1007/s15010-011-0127-3

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