Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance

C. Sarrecchia; V. Svicher; A. Volpi; R. Salpini; L. Ceccarelli; P. Sordillo; A. Bertoli; C. F. Perno; M. Andreoni

doi:10.1007/s15010-011-0127-3

Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance

C. Sarrecchia, V. Svicher, A. Volpi, R. Salpini, L. Ceccarelli, P. Sordillo, A. Bertoli, C. F. Perno, M. Andreoni

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article

Abstract

We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log ₁₀ IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success (serum HBV DNA

Original language	English
Pages (from-to)	367-370
Number of pages	4
Journal	Infection
Volume	39
Issue number	4
DOIs	https://doi.org/10.1007/s15010-011-0127-3
Publication status	Published - Aug 2011

Fingerprint

Keywords

Drug resistance
Entecavir
Hepatitis B
Immunocompromised
Therapy

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Cite this

Sarrecchia, C., Svicher, V., Volpi, A., Salpini, R., Ceccarelli, L., Sordillo, P., Bertoli, A., Perno, C. F., & Andreoni, M. (2011). Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. Infection, 39(4), 367-370. https://doi.org/10.1007/s15010-011-0127-3

Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. / Sarrecchia, C.; Svicher, V.; Volpi, A.; Salpini, R.; Ceccarelli, L.; Sordillo, P.; Bertoli, A.; Perno, C. F.; Andreoni, M.

In: Infection, Vol. 39, No. 4, 08.2011, p. 367-370.

Research output: Contribution to journal › Article

Sarrecchia, C, Svicher, V, Volpi, A, Salpini, R, Ceccarelli, L, Sordillo, P, Bertoli, A, Perno, CF & Andreoni, M 2011, 'Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance', Infection, vol. 39, no. 4, pp. 367-370. https://doi.org/10.1007/s15010-011-0127-3

@article{05397ae4a1b242dd957205d20e184f32,

title = "Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance",

abstract = "We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log 10 IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success (serum HBV DNA",

keywords = "Drug resistance, Entecavir, Hepatitis B, Immunocompromised, Therapy",

author = "C. Sarrecchia and V. Svicher and A. Volpi and R. Salpini and L. Ceccarelli and P. Sordillo and A. Bertoli and Perno, {C. F.} and M. Andreoni",

year = "2011",

month = aug

doi = "10.1007/s15010-011-0127-3",

language = "English",

volume = "39",

pages = "367--370",

journal = "Infection",

issn = "0300-8126",

publisher = "Urban und Vogel GmbH",

number = "4",

}

TY - JOUR

T1 - Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance

AU - Sarrecchia, C.

AU - Svicher, V.

AU - Volpi, A.

AU - Salpini, R.

AU - Ceccarelli, L.

AU - Sordillo, P.

AU - Bertoli, A.

AU - Perno, C. F.

AU - Andreoni, M.

PY - 2011/8

Y1 - 2011/8

N2 - We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log 10 IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success (serum HBV DNA

AB - We report a case of an immunocompromised patient affected by chronic hepatitis B virus (HBV) with high basal HBV viremia (>8 log 10 IU/ml) who failed an entecavir regimen, despite the absence of primary or secondary drug resistance mutations. The patient achieved sustained virological success (serum HBV DNA

KW - Drug resistance

KW - Entecavir

KW - Hepatitis B

KW - Immunocompromised

KW - Therapy

UR - http://www.scopus.com/inward/record.url?scp=80655144427&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80655144427&partnerID=8YFLogxK

U2 - 10.1007/s15010-011-0127-3

DO - 10.1007/s15010-011-0127-3

M3 - Article

C2 - 21674358

AN - SCOPUS:80655144427

VL - 39

SP - 367

EP - 370

JO - Infection

JF - Infection

SN - 0300-8126

IS - 4

ER -

Access to Document

10.1007/s15010-011-0127-3