Successful treatment of coronary artery spasm following coronary artery bypass grafting.

F. Donatelli, M. A. Mariani, M. Pocar, M. Triggiani, S. Pelenghi, A. Grossi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A case of coronary artery spasm developed 6 hours after myocardial revascularization inducing both hemodynamic and electrocardiographic changes, is reported. The spasm was documented by coronary angiography, and it was not reversed by intracoronary infusion of isosorbide dinitrate. Intravenous infusion of nifedipine (initial dose of 0.0104 mg/min to final dose of 0.0208 mg/min), along with infusion of glyceronitrate (1.0 micrograms/kg/min) was able to significantly improve hemodynamic impairment and to reverse electrocardiographic changes in 12 hours. Coronary angiography, repeated in postoperative day 3, after 48 hours of continuous nifedipine infusion, showed a resolution of coronary spasm. There was no evidence of myocardial infarction as resulted from total CPK and MB isoenzyme release. Nifedipine infusion was gradually reduced as oral administration of slow release nifedipine (40 mg twice daily) was started. The combined intravenous infusion of glyceronitrate and nifedipine seems to be able to control and overcome coronary artery spasm following coronary surgery.

Original languageEnglish
Pages (from-to)601-605
Number of pages5
JournalCardiologia
Volume38
Issue number9
Publication statusPublished - Sep 1993

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Spasm
Nifedipine
Coronary Artery Bypass
Coronary Vessels
Coronary Angiography
Intravenous Infusions
Hemodynamics
Isosorbide Dinitrate
Therapeutics
MB Form Creatine Kinase
Myocardial Revascularization
Oral Administration
Myocardial Infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Donatelli, F., Mariani, M. A., Pocar, M., Triggiani, M., Pelenghi, S., & Grossi, A. (1993). Successful treatment of coronary artery spasm following coronary artery bypass grafting. Cardiologia, 38(9), 601-605.

Successful treatment of coronary artery spasm following coronary artery bypass grafting. / Donatelli, F.; Mariani, M. A.; Pocar, M.; Triggiani, M.; Pelenghi, S.; Grossi, A.

In: Cardiologia, Vol. 38, No. 9, 09.1993, p. 601-605.

Research output: Contribution to journalArticle

Donatelli, F, Mariani, MA, Pocar, M, Triggiani, M, Pelenghi, S & Grossi, A 1993, 'Successful treatment of coronary artery spasm following coronary artery bypass grafting.', Cardiologia, vol. 38, no. 9, pp. 601-605.
Donatelli F, Mariani MA, Pocar M, Triggiani M, Pelenghi S, Grossi A. Successful treatment of coronary artery spasm following coronary artery bypass grafting. Cardiologia. 1993 Sep;38(9):601-605.
Donatelli, F. ; Mariani, M. A. ; Pocar, M. ; Triggiani, M. ; Pelenghi, S. ; Grossi, A. / Successful treatment of coronary artery spasm following coronary artery bypass grafting. In: Cardiologia. 1993 ; Vol. 38, No. 9. pp. 601-605.
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