Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: A double blind, controlled study

F. Francini-Pesenti, F. Brocadello, D. Beltramolli, M. Nardi, L. Caregaro

Research output: Contribution to journalArticlepeer-review

Abstract

Previous clinical studies have shown that oral administration of sugar cane policosanol (SCP) reduces plasma total cholesterol and low-density lipoprotein cholesterol levels. A double blind, randomized, placebo controlled trial was performed in hypercholesterolaemic, diet-resistant patients. Seventy patients meeting the selection criteria were enrolled. Each subject was treated with policosanol 10 mg/d in addition to a dietetic regimen for 8 weeks. At the start and at the end of the study body weight, body mass index (BMI), total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides (TG) plasma levels were measured. Thirty-three subjects in the policosanol and Thirty-one subjects in the control group completed the study. During the study body mass index, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides plasma levels did not change significantly within and between groups. In conclusion, sugar cane policosanol at a dose of 10 mg/d showed no lipid lowering effects in subjects with primitive, diet-resistant hypercholesterolaemia.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalComplementary Therapies in Medicine
Volume16
Issue number2
DOIs
Publication statusPublished - Apr 2008

Keywords

  • Hypercholesterolaemia
  • Long-chain aliphatic primary alcohols
  • Policosanol
  • Sugar cane wax

ASJC Scopus subject areas

  • Medicine(all)
  • Complementary and alternative medicine
  • Nursing(all)

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