Sulfonylurea treatment in a girl with neonatal diabetes (KCNJ11 R201H) and celiac disease: Impact of low compliance to the gluten free diet

Maurizio Delvecchio, Clara Zecchino, Maria Felicia Faienza, Angelo Acquafredda, Fabrizio Barbetti, Luciano Cavallo

Research output: Contribution to journalArticlepeer-review

Abstract

A girl with celiac disease and KCNJ11 mutation was transferred to glibenclamide when 19.8 years old. When her compliance to the gluten free diet worsened, her metabolic control deteriorated. Since glibenclamide is absorbed in the intestine, its absorption seems to be impaired by chronic malabsorption, increasing the risk of hyperglycaemia.

Original languageEnglish
Pages (from-to)332-334
Number of pages3
JournalDiabetes Research and Clinical Practice
Volume84
Issue number3
DOIs
Publication statusPublished - Jun 2009

Keywords

  • Celiac disease
  • Gluten free diet
  • KCNJ11
  • Neonatal diabetes
  • Sulfonylurea

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

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