Sunscreens and cutaneous malignant melanoma: An Italian case-control study

Luigi Naldi, Silvano Gallus, G. Lorenzo Imberti, Tullio Cainelli, Eva Negri, Carlo La Vecchia

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The possible relation between use of sunscreens and the risk of cutaneous malignant melanoma (CMM) was investigated in a case-control study conducted in 27 Italian centres on 542 incident, histologically confirmed cases and 538 controls admitted for acute, other than neoplastic or dermatologic conditions. Compared with subjects reporting never sunscreen use, the multivariate odds ratios (OR), after allowance for age, sex, geographic area, education, skin, eye and hair colour, freckles, number of naevi, history of sunburns, tanning pattern and duration of sunny vacations, were 0.97 .(95% confidence interval [CI] 0.69 to 1.35) for those reporting 'sometimes' and 0.80 (95% CI 0.54 to 1.17) for those reporting 'often' sunscreen use. With reference to type of product most frequently used, the ORs were 0.96 (95% Cl 0.52 to 1.77) for minimal, 0.90 (95% CI 0.63 to 1.28) for moderate and 1.41 (95% CI 0.85 to 2.35) for high sunburn protection factor. With reference to duration of use, the OR was 0.86 (95% CI 0.58 to 1.29) for use started since ≥20 years. None of the corresponding trends in risks were significant. The ORs for sunscreen use were similar across strata of major identified covariates and, if anything, tended to decline after multivariate analysis. The present findings confirm that sunscreen use, as currently adopted in Italy, is not appreciably related to subsequent CMM risk. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)879-882
Number of pages4
JournalInternational Journal of Cancer
Volume86
Issue number6
DOIs
Publication statusPublished - Jun 15 2000

Fingerprint

Sunscreening Agents
Case-Control Studies
Confidence Intervals
Sunburn
Odds Ratio
Hair Color
Eye Color
Tanning
Skin Pigmentation
Melanosis
Nevus
Italy
Multivariate Analysis
Cutaneous Malignant Melanoma
Education

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Sunscreens and cutaneous malignant melanoma : An Italian case-control study. / Naldi, Luigi; Gallus, Silvano; Imberti, G. Lorenzo; Cainelli, Tullio; Negri, Eva; La Vecchia, Carlo.

In: International Journal of Cancer, Vol. 86, No. 6, 15.06.2000, p. 879-882.

Research output: Contribution to journalArticle

Naldi, Luigi ; Gallus, Silvano ; Imberti, G. Lorenzo ; Cainelli, Tullio ; Negri, Eva ; La Vecchia, Carlo. / Sunscreens and cutaneous malignant melanoma : An Italian case-control study. In: International Journal of Cancer. 2000 ; Vol. 86, No. 6. pp. 879-882.
@article{0f0afa8e178b4e419621598d457f8a1e,
title = "Sunscreens and cutaneous malignant melanoma: An Italian case-control study",
abstract = "The possible relation between use of sunscreens and the risk of cutaneous malignant melanoma (CMM) was investigated in a case-control study conducted in 27 Italian centres on 542 incident, histologically confirmed cases and 538 controls admitted for acute, other than neoplastic or dermatologic conditions. Compared with subjects reporting never sunscreen use, the multivariate odds ratios (OR), after allowance for age, sex, geographic area, education, skin, eye and hair colour, freckles, number of naevi, history of sunburns, tanning pattern and duration of sunny vacations, were 0.97 .(95{\%} confidence interval [CI] 0.69 to 1.35) for those reporting 'sometimes' and 0.80 (95{\%} CI 0.54 to 1.17) for those reporting 'often' sunscreen use. With reference to type of product most frequently used, the ORs were 0.96 (95{\%} Cl 0.52 to 1.77) for minimal, 0.90 (95{\%} CI 0.63 to 1.28) for moderate and 1.41 (95{\%} CI 0.85 to 2.35) for high sunburn protection factor. With reference to duration of use, the OR was 0.86 (95{\%} CI 0.58 to 1.29) for use started since ≥20 years. None of the corresponding trends in risks were significant. The ORs for sunscreen use were similar across strata of major identified covariates and, if anything, tended to decline after multivariate analysis. The present findings confirm that sunscreen use, as currently adopted in Italy, is not appreciably related to subsequent CMM risk. (C) 2000 Wiley-Liss, Inc.",
author = "Luigi Naldi and Silvano Gallus and Imberti, {G. Lorenzo} and Tullio Cainelli and Eva Negri and {La Vecchia}, Carlo",
year = "2000",
month = "6",
day = "15",
doi = "10.1002/(SICI)1097-0215(20000615)86:6<879::AID-IJC19>3.0.CO;2-N",
language = "English",
volume = "86",
pages = "879--882",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Sunscreens and cutaneous malignant melanoma

T2 - An Italian case-control study

AU - Naldi, Luigi

AU - Gallus, Silvano

AU - Imberti, G. Lorenzo

AU - Cainelli, Tullio

AU - Negri, Eva

AU - La Vecchia, Carlo

PY - 2000/6/15

Y1 - 2000/6/15

N2 - The possible relation between use of sunscreens and the risk of cutaneous malignant melanoma (CMM) was investigated in a case-control study conducted in 27 Italian centres on 542 incident, histologically confirmed cases and 538 controls admitted for acute, other than neoplastic or dermatologic conditions. Compared with subjects reporting never sunscreen use, the multivariate odds ratios (OR), after allowance for age, sex, geographic area, education, skin, eye and hair colour, freckles, number of naevi, history of sunburns, tanning pattern and duration of sunny vacations, were 0.97 .(95% confidence interval [CI] 0.69 to 1.35) for those reporting 'sometimes' and 0.80 (95% CI 0.54 to 1.17) for those reporting 'often' sunscreen use. With reference to type of product most frequently used, the ORs were 0.96 (95% Cl 0.52 to 1.77) for minimal, 0.90 (95% CI 0.63 to 1.28) for moderate and 1.41 (95% CI 0.85 to 2.35) for high sunburn protection factor. With reference to duration of use, the OR was 0.86 (95% CI 0.58 to 1.29) for use started since ≥20 years. None of the corresponding trends in risks were significant. The ORs for sunscreen use were similar across strata of major identified covariates and, if anything, tended to decline after multivariate analysis. The present findings confirm that sunscreen use, as currently adopted in Italy, is not appreciably related to subsequent CMM risk. (C) 2000 Wiley-Liss, Inc.

AB - The possible relation between use of sunscreens and the risk of cutaneous malignant melanoma (CMM) was investigated in a case-control study conducted in 27 Italian centres on 542 incident, histologically confirmed cases and 538 controls admitted for acute, other than neoplastic or dermatologic conditions. Compared with subjects reporting never sunscreen use, the multivariate odds ratios (OR), after allowance for age, sex, geographic area, education, skin, eye and hair colour, freckles, number of naevi, history of sunburns, tanning pattern and duration of sunny vacations, were 0.97 .(95% confidence interval [CI] 0.69 to 1.35) for those reporting 'sometimes' and 0.80 (95% CI 0.54 to 1.17) for those reporting 'often' sunscreen use. With reference to type of product most frequently used, the ORs were 0.96 (95% Cl 0.52 to 1.77) for minimal, 0.90 (95% CI 0.63 to 1.28) for moderate and 1.41 (95% CI 0.85 to 2.35) for high sunburn protection factor. With reference to duration of use, the OR was 0.86 (95% CI 0.58 to 1.29) for use started since ≥20 years. None of the corresponding trends in risks were significant. The ORs for sunscreen use were similar across strata of major identified covariates and, if anything, tended to decline after multivariate analysis. The present findings confirm that sunscreen use, as currently adopted in Italy, is not appreciably related to subsequent CMM risk. (C) 2000 Wiley-Liss, Inc.

UR - http://www.scopus.com/inward/record.url?scp=0034660601&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034660601&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1097-0215(20000615)86:6<879::AID-IJC19>3.0.CO;2-N

DO - 10.1002/(SICI)1097-0215(20000615)86:6<879::AID-IJC19>3.0.CO;2-N

M3 - Article

C2 - 10842205

AN - SCOPUS:0034660601

VL - 86

SP - 879

EP - 882

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 6

ER -