Abstract
The aim of this study was to determine whether the systematic use of SPECT can increase the reported low sensitivity of somatostatin receptor scintigraphy (SRS) in detecting insulinomas. Methods: Fourteen patients were evaluated. After 111Inpentetreotide injection (~250 MBq intravenously), abdominal SPECT images were obtained at 4 h and multiple planar images were obtained at 4 and 24 h. MRI and CT were performed within 1 mo of SRS. Sixteen tumors were histologically verified after surgery in 14 patients. Results: SPECT revealed 14 lesions in 12 patients (sensitivity, 87.5%), both planar SRS and MRI revealed 7 tumors in 7 patients (sensitivity, 43.8%), and CT revealed only 5 lesions in 4 patients (sensitivity, 31.3%). Moreover, in 4 patients SPECT was the only examination with positive findings. Conclusion: SPECT at 4 h is mandatory for preoperative detection of insulinomas using SRS because the images are more sensitive than planar images and are superior to images from other conventional methods.
Original language | English |
---|---|
Pages (from-to) | 459-462 |
Number of pages | 4 |
Journal | Journal of Nuclear Medicine |
Volume | 41 |
Issue number | 3 |
Publication status | Published - 2000 |
Keywords
- Insulinomas
- Somatostatin receptor scintigraphy
- SPECT
ASJC Scopus subject areas
- Radiological and Ultrasound Technology