11C-Choline PET/CT and PSA kinetics

Paolo Castellucci, Maria Picchio

Research output: Contribution to journalArticlepeer-review


The role of PET/CTwith radiolabelled 18F-choline or 11C-choline in patients with prostate cancer after primary treatment has not been established yet and there are no guidelines on the appropriate use of this emerging modality. According to the literature, choline PET/CT may have a role in restaging the disease in patients with biochemical relapse for the detection of local and/or lymph node and/or distant recurrence. The aim of this brief review is to summarize the results of the most relevant published studies with particular focus on the relationship between prostate-specific antigen levels and kinetics and the sensitivity of choline PET/CT for optimizing the selection of patients who may benefit the most from this diagnostic procedure, especially early after biochemical recurrence.

Original languageEnglish
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Issue numberSUPPL. 1
Publication statusPublished - 2013


  • Choline
  • PET/CT
  • Prostate cancer
  • PSA kinetics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)


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