123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy

A. Antonini, R. Benti, R. De Notaris, S. Tesei, A. Zecchinelli, G. Sacilotto, N. Meucci, M. Canesi, C. Mariani, G. Pezzoli, P. Gerundini

Research output: Contribution to journalArticle

Abstract

We used SPECT and the tracer 123I-Ioflupane to measure dopamine transporter (DAT) binding in the caudate nucleus and the putamen of 70 patients with Parkinson's disease (PD), 10 with multiple system atrophy (MSA-P type), and 10 with progressive supranuclear palsy (PSP). Data were compared with 12 age-matched control subjects. We found significant reductions in mean striatal values in all three forms of parkinsonism. However, decrements were significantly greater in PSP (0.51±0.39, p

Original languageEnglish
Pages (from-to)149-150
Number of pages2
JournalNeurological Sciences
Volume24
Issue number3
DOIs
Publication statusPublished - Oct 2003

Fingerprint

Progressive Supranuclear Palsy
Multiple System Atrophy
Corpus Striatum
Dopamine Plasma Membrane Transport Proteins
Single-Photon Emission-Computed Tomography
Parkinson Disease
Caudate Nucleus
Putamen
Parkinsonian Disorders
ioflupane
Parkinson Disease 10

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. / Antonini, A.; Benti, R.; De Notaris, R.; Tesei, S.; Zecchinelli, A.; Sacilotto, G.; Meucci, N.; Canesi, M.; Mariani, C.; Pezzoli, G.; Gerundini, P.

In: Neurological Sciences, Vol. 24, No. 3, 10.2003, p. 149-150.

Research output: Contribution to journalArticle

Antonini, A, Benti, R, De Notaris, R, Tesei, S, Zecchinelli, A, Sacilotto, G, Meucci, N, Canesi, M, Mariani, C, Pezzoli, G & Gerundini, P 2003, '123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy', Neurological Sciences, vol. 24, no. 3, pp. 149-150. https://doi.org/10.1007/s10072-003-0103-5
Antonini, A. ; Benti, R. ; De Notaris, R. ; Tesei, S. ; Zecchinelli, A. ; Sacilotto, G. ; Meucci, N. ; Canesi, M. ; Mariani, C. ; Pezzoli, G. ; Gerundini, P. / 123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. In: Neurological Sciences. 2003 ; Vol. 24, No. 3. pp. 149-150.
@article{da577944b242453e8c8b6d421931f7dc,
title = "123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy",
abstract = "We used SPECT and the tracer 123I-Ioflupane to measure dopamine transporter (DAT) binding in the caudate nucleus and the putamen of 70 patients with Parkinson's disease (PD), 10 with multiple system atrophy (MSA-P type), and 10 with progressive supranuclear palsy (PSP). Data were compared with 12 age-matched control subjects. We found significant reductions in mean striatal values in all three forms of parkinsonism. However, decrements were significantly greater in PSP (0.51±0.39, p",
author = "A. Antonini and R. Benti and {De Notaris}, R. and S. Tesei and A. Zecchinelli and G. Sacilotto and N. Meucci and M. Canesi and C. Mariani and G. Pezzoli and P. Gerundini",
year = "2003",
month = "10",
doi = "10.1007/s10072-003-0103-5",
language = "English",
volume = "24",
pages = "149--150",
journal = "Neurological Sciences",
issn = "1590-1874",
publisher = "Springer-Verlag Italia s.r.l.",
number = "3",

}

TY - JOUR

T1 - 123I-Ioflupane/SPECT binding to striatal dopamine transporter (DAT) uptake in patients with Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy

AU - Antonini, A.

AU - Benti, R.

AU - De Notaris, R.

AU - Tesei, S.

AU - Zecchinelli, A.

AU - Sacilotto, G.

AU - Meucci, N.

AU - Canesi, M.

AU - Mariani, C.

AU - Pezzoli, G.

AU - Gerundini, P.

PY - 2003/10

Y1 - 2003/10

N2 - We used SPECT and the tracer 123I-Ioflupane to measure dopamine transporter (DAT) binding in the caudate nucleus and the putamen of 70 patients with Parkinson's disease (PD), 10 with multiple system atrophy (MSA-P type), and 10 with progressive supranuclear palsy (PSP). Data were compared with 12 age-matched control subjects. We found significant reductions in mean striatal values in all three forms of parkinsonism. However, decrements were significantly greater in PSP (0.51±0.39, p

AB - We used SPECT and the tracer 123I-Ioflupane to measure dopamine transporter (DAT) binding in the caudate nucleus and the putamen of 70 patients with Parkinson's disease (PD), 10 with multiple system atrophy (MSA-P type), and 10 with progressive supranuclear palsy (PSP). Data were compared with 12 age-matched control subjects. We found significant reductions in mean striatal values in all three forms of parkinsonism. However, decrements were significantly greater in PSP (0.51±0.39, p

UR - http://www.scopus.com/inward/record.url?scp=0142248498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0142248498&partnerID=8YFLogxK

U2 - 10.1007/s10072-003-0103-5

DO - 10.1007/s10072-003-0103-5

M3 - Article

C2 - 14598060

AN - SCOPUS:0142248498

VL - 24

SP - 149

EP - 150

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

IS - 3

ER -