18F-FCH and 90Y PET/CT data for the early evaluation of HCC radioembolisation

Research output: Contribution to journalArticle

Abstract

In the recent years, there has been a growing interest in the use of 90Y-microspheres for regional HCC therapy with the therapy response assessment as a crucial point. Because morphologic imaging performance is limited in this set, functional metabolic imaging method, which can early and reliably distinguish between therapy responders and non-responders, is highly needed. The purpose of this pictorial essay was to demonstrate the potential value of 18F-fluoro-choline positron emission tomography (18F-FCH-PET)/CT in detecting and early-therapy monitoring of HCC patients who underwent to TARE, by showing exemplary HCC patients who underwent 18F-FCH-PET/CT as part of their routine clinical work-up in our institution. In addition, we aimed to illustrate that the mapping of the 90Y-microspheres distribution provided by 90Y-PET/CT may anticipate information about treatment response.

Original languageEnglish
Pages (from-to)357-367
Number of pages11
JournalClinical and Translational Imaging
Volume6
Issue number5
DOIs
Publication statusPublished - Oct 1 2018

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Microspheres
Positron-Emission Tomography
Physiologic Monitoring
Therapeutics
Secondary Prevention
fluorocholine
fluoromethylcholine

Keywords

  • F-FCH-PET/CT
  • Y PET/CT
  • Early response to therapy
  • HCC
  • Hepatocarcinoma
  • Radioembolisation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

18F-FCH and 90Y PET/CT data for the early evaluation of HCC radioembolisation. / Ferrari, Cristina; Di Palo, Alessandra; Niccoli Asabella, Artor; Didonna, Vittorio; Ranieri, Girolamo; Gadaleta, Cosmo Damiano; Rubini, Giuseppe.

In: Clinical and Translational Imaging, Vol. 6, No. 5, 01.10.2018, p. 357-367.

Research output: Contribution to journalArticle

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