18F-FCH and 90Y PET/CT data for the early evaluation of HCC radioembolisation

Cristina Ferrari, Alessandra Di Palo, Artor Niccoli Asabella, Vittorio Didonna, Girolamo Ranieri, Cosmo Damiano Gadaleta, Giuseppe Rubini

Research output: Contribution to journalArticlepeer-review


In the recent years, there has been a growing interest in the use of 90Y-microspheres for regional HCC therapy with the therapy response assessment as a crucial point. Because morphologic imaging performance is limited in this set, functional metabolic imaging method, which can early and reliably distinguish between therapy responders and non-responders, is highly needed. The purpose of this pictorial essay was to demonstrate the potential value of 18F-fluoro-choline positron emission tomography (18F-FCH-PET)/CT in detecting and early-therapy monitoring of HCC patients who underwent to TARE, by showing exemplary HCC patients who underwent 18F-FCH-PET/CT as part of their routine clinical work-up in our institution. In addition, we aimed to illustrate that the mapping of the 90Y-microspheres distribution provided by 90Y-PET/CT may anticipate information about treatment response.

Original languageEnglish
Pages (from-to)357-367
Number of pages11
JournalClinical and Translational Imaging
Issue number5
Publication statusPublished - Oct 1 2018


  • Y PET/CT
  • Early response to therapy
  • HCC
  • Hepatocarcinoma
  • Radioembolisation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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