99mTc-MIBI in the evaluation of breast cancer biology

Silvana Del Vecchio, Antonella Zannetti, Rosa Fonti, Francesca Iommelli, Marco Salvatore

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Scintigraphic in vivo evaluation of complex cellular processes such as proliferation, apoptosis, receptor/ligand interactions, transport of substrates and metabolism of nutrients in human cancers is a wide and continuing evolving area of investigation in nuclear medicine (Denoyer et al. 2006; Been et al. 2004; Corsten et al. 2006; Weissleder 2006). A major purpose in this area is the non-invasive detection of well-known biochemical, molecular and histological markers of tumor aggressiveness, invasiveness and resistance to therapy, which may provide rational criteria for a fine tuning of therapeutic strategies in individual patients.

Original languageEnglish
Title of host publicationBreast Cancer: Nuclear Medicine in Diagnosis and Therapeutic Options
PublisherSpringer Berlin Heidelberg
Pages71-81
Number of pages11
ISBN (Print)9783540367802
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Medicine(all)

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