TY - JOUR
T1 - Superficial siderosis due to dural defect with thoracic spinal cord herniation
AU - Boncoraglio, Giorgio B.
AU - Ballabio, Elena
AU - Erbetta, Alessandra
AU - Prada, Francesco
AU - Savoiardo, Mario
AU - Parati, Eugenio A.
PY - 2012/1/15
Y1 - 2012/1/15
N2 - Superficial siderosis (SS) of the central nervous system is a rare disorder caused by chronic or recurrent hemorrhages into the subarachnoid space with hemosiderin and ferritin deposition, which leads to neuronal damage. The source of bleeding remains unknown in 50% of cases. Recently, attention has been focused on fluid-filled collection in the spinal canal, suggesting the presence of a dural defect which may be the bleeding point. We present a patient with SS and spinal extradural fluid collection due to midthoracic dural defect with spinal cord herniation. The reduction of the spinal cord herniation and the repair of the dural defect resulted in the disappearance of the fluid collection and cerebrospinal fluid abnormalities. The case here reported is, to our knowledge, the first case of spinal cord herniation presenting with SS and confirms the key role played by dural lacerations in the pathogenesis of both SS and spinal cord herniation. The search for dural lacerations should be one of the primary aims in patients with SS.
AB - Superficial siderosis (SS) of the central nervous system is a rare disorder caused by chronic or recurrent hemorrhages into the subarachnoid space with hemosiderin and ferritin deposition, which leads to neuronal damage. The source of bleeding remains unknown in 50% of cases. Recently, attention has been focused on fluid-filled collection in the spinal canal, suggesting the presence of a dural defect which may be the bleeding point. We present a patient with SS and spinal extradural fluid collection due to midthoracic dural defect with spinal cord herniation. The reduction of the spinal cord herniation and the repair of the dural defect resulted in the disappearance of the fluid collection and cerebrospinal fluid abnormalities. The case here reported is, to our knowledge, the first case of spinal cord herniation presenting with SS and confirms the key role played by dural lacerations in the pathogenesis of both SS and spinal cord herniation. The search for dural lacerations should be one of the primary aims in patients with SS.
KW - Dural defect
KW - Neuroradiology
KW - Neurosurgery
KW - Spinal cord herniation
KW - Superficial siderosis
UR - http://www.scopus.com/inward/record.url?scp=84860404005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860404005&partnerID=8YFLogxK
U2 - 10.1016/j.jns.2011.07.034
DO - 10.1016/j.jns.2011.07.034
M3 - Article
C2 - 21868040
AN - SCOPUS:84860404005
VL - 312
SP - 170
EP - 172
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
IS - 1-2
ER -