Superovulation and intrauterine insemination vs. superovulation alone in the treatment of unexplained infertility: A randomized study

Luisa Arcaini, Stefano Bianchi, Andrea Baglioni, Maurizio Marchini, Luca Tozzi, Luigi Fedele

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To assess whether intrauterine insemination (IUI) improves the fertility rates in women with un explained infertility. STUDY DESIGN: We recruited 68 women with un explained infertility and al located them randomly to treatment with three to five cycles of super ovulation plus IUI (36 patients) or superovulation alone (32 patients). Superovulation was obtained with clomiphene citrate, human menopausal gonadotropins and human chorionic gonadotropins. RESULTS: The cycle fecundity rate was 10% in patients who underwent superovulation alone and 19% in those treated with superovulation plus IUI (P <.05). CONCLUSION: Our results demonstrate that superovulation plus IUI is more effective than superovulation alone in the treatment of unexplained infertility.

Original languageEnglish
Pages (from-to)614-618
Number of pages5
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume41
Issue number8
Publication statusPublished - Aug 1996

Keywords

  • infertility, female
  • insemination, artificial, husband

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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