Supplemented amino acids may enhance the walking recovery of elderly subjects after hip fracture surgery

Roberto Aquilani, Carlo Zuccarelli Ginetto, Carla Rutili, Pietro Pisano, Evasio Pasini, Eleonora Baldissarro, Manuela Verri, Federica Boschi

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study was to investigate whether supplemented essential amino acids (EAAs) could enhance rehabilitation therapy (Rehab) for recovery of walking capacity in subjects after hip fracture surgery (HFS). Eighty-three elderly subjects with HFS (20 ± 11 days after acute trauma) were eligible for the study and randomized to receive Rehab only (Rehab; n = 27), Rehab + placebo (RP; n = 28) or Rehab + EAAs (RE 8 g/day; n = 28). The patients' walking capacity (m) was measured by 6-min walking distance (6MWD) at admission and at discharge (median 66 days after admission). All patient groups were treated with the same Rehab (2 sessions/day × 5 days/week). The results showed that the gain in 6MWD was higher in RE than in Rehab and RP (p = 0.034; p = 0.024). The study shows that EAA supplementation can enhance walking recovery rate in subjects with HFS.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalAging Clin. Exp. Res.
Volume31
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Aged
  • Aged, 80 and over
  • Amino Acids, Essential/therapeutic use
  • Female
  • Hip Fractures/rehabilitation
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Patient Discharge
  • Walking/physiology

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