Supracricoid partial laryngectomies after radiation failure: A multi-institutional series

Raul Pellini, Barbara Pichi, Paolo Ruscito, Alberto Rinaldi Ceroni, Umberto Caliceti, Giuseppe Rizzotto, Antonio Pazzaia, Pasquale Laudadio, Cesare Piazza, Giorgio Peretti, Diana Giannarelli, Giuseppe Spriano

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background. Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs). Methods. A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases. Results. Disease-free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases. Conclusions. SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.

Original languageEnglish
Pages (from-to)372-379
Number of pages8
JournalHead and Neck
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 2008

Fingerprint

Laryngectomy
Radiation
Radiotherapy
Recurrence
Tongue Neoplasms
Organ Preservation
Laryngeal Neoplasms
Deglutition
Disease-Free Survival
Morbidity
Therapeutics

Keywords

  • Laryngeal cancer
  • Organ preservation surgery
  • Partial laryngectomy
  • Radiation failure
  • Supracricoid laryngectomy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Pellini, R., Pichi, B., Ruscito, P., Ceroni, A. R., Caliceti, U., Rizzotto, G., ... Spriano, G. (2008). Supracricoid partial laryngectomies after radiation failure: A multi-institutional series. Head and Neck, 30(3), 372-379. https://doi.org/10.1002/hed.20709

Supracricoid partial laryngectomies after radiation failure : A multi-institutional series. / Pellini, Raul; Pichi, Barbara; Ruscito, Paolo; Ceroni, Alberto Rinaldi; Caliceti, Umberto; Rizzotto, Giuseppe; Pazzaia, Antonio; Laudadio, Pasquale; Piazza, Cesare; Peretti, Giorgio; Giannarelli, Diana; Spriano, Giuseppe.

In: Head and Neck, Vol. 30, No. 3, 03.2008, p. 372-379.

Research output: Contribution to journalArticle

Pellini, R, Pichi, B, Ruscito, P, Ceroni, AR, Caliceti, U, Rizzotto, G, Pazzaia, A, Laudadio, P, Piazza, C, Peretti, G, Giannarelli, D & Spriano, G 2008, 'Supracricoid partial laryngectomies after radiation failure: A multi-institutional series', Head and Neck, vol. 30, no. 3, pp. 372-379. https://doi.org/10.1002/hed.20709
Pellini R, Pichi B, Ruscito P, Ceroni AR, Caliceti U, Rizzotto G et al. Supracricoid partial laryngectomies after radiation failure: A multi-institutional series. Head and Neck. 2008 Mar;30(3):372-379. https://doi.org/10.1002/hed.20709
Pellini, Raul ; Pichi, Barbara ; Ruscito, Paolo ; Ceroni, Alberto Rinaldi ; Caliceti, Umberto ; Rizzotto, Giuseppe ; Pazzaia, Antonio ; Laudadio, Pasquale ; Piazza, Cesare ; Peretti, Giorgio ; Giannarelli, Diana ; Spriano, Giuseppe. / Supracricoid partial laryngectomies after radiation failure : A multi-institutional series. In: Head and Neck. 2008 ; Vol. 30, No. 3. pp. 372-379.
@article{2191b85f49ef4b91ab8c6f454c847a97,
title = "Supracricoid partial laryngectomies after radiation failure: A multi-institutional series",
abstract = "Background. Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs). Methods. A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases. Results. Disease-free survival at 3 and 5 years were 95.5{\%}. Early and late postoperative complications occurred in 27{\%} and 17.9{\%} of cases. Decannulation and satisfactory swallowing were achieved in 97.4{\%} of cases. Conclusions. SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.",
keywords = "Laryngeal cancer, Organ preservation surgery, Partial laryngectomy, Radiation failure, Supracricoid laryngectomy",
author = "Raul Pellini and Barbara Pichi and Paolo Ruscito and Ceroni, {Alberto Rinaldi} and Umberto Caliceti and Giuseppe Rizzotto and Antonio Pazzaia and Pasquale Laudadio and Cesare Piazza and Giorgio Peretti and Diana Giannarelli and Giuseppe Spriano",
year = "2008",
month = "3",
doi = "10.1002/hed.20709",
language = "English",
volume = "30",
pages = "372--379",
journal = "Head and Neck Surgery",
issn = "1043-3074",
publisher = "Wiley-Liss Inc.",
number = "3",

}

TY - JOUR

T1 - Supracricoid partial laryngectomies after radiation failure

T2 - A multi-institutional series

AU - Pellini, Raul

AU - Pichi, Barbara

AU - Ruscito, Paolo

AU - Ceroni, Alberto Rinaldi

AU - Caliceti, Umberto

AU - Rizzotto, Giuseppe

AU - Pazzaia, Antonio

AU - Laudadio, Pasquale

AU - Piazza, Cesare

AU - Peretti, Giorgio

AU - Giannarelli, Diana

AU - Spriano, Giuseppe

PY - 2008/3

Y1 - 2008/3

N2 - Background. Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs). Methods. A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases. Results. Disease-free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases. Conclusions. SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.

AB - Background. Radiation therapy (RT) is one of the gold standard treatments for early laryngeal cancer, and total laryngectomy is still the most applied surgical procedure after failure. Selected recurrences can be managed by supracricoid partial laryngectomies (SCPLs). Methods. A multi-institutional retrospective analysis was carried out in 78 consecutive patients treated by SCPLs for the recurrence of glottic-supraglottic cancer after RT. Cricohyoidoepiglottopexy was performed in 62, and cricohyoidopexy (CHP) in 16 cases. Results. Disease-free survival at 3 and 5 years were 95.5%. Early and late postoperative complications occurred in 27% and 17.9% of cases. Decannulation and satisfactory swallowing were achieved in 97.4% of cases. Conclusions. SCPLs represent effective surgical organ-preservation strategies in the treatment of selected recurrences after RT failure, resulting in a good local control as well as functional recovery with acceptable morbidity, despite a complication rate which is not negligible.

KW - Laryngeal cancer

KW - Organ preservation surgery

KW - Partial laryngectomy

KW - Radiation failure

KW - Supracricoid laryngectomy

UR - http://www.scopus.com/inward/record.url?scp=41649119047&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41649119047&partnerID=8YFLogxK

U2 - 10.1002/hed.20709

DO - 10.1002/hed.20709

M3 - Article

C2 - 17972314

AN - SCOPUS:41649119047

VL - 30

SP - 372

EP - 379

JO - Head and Neck Surgery

JF - Head and Neck Surgery

SN - 1043-3074

IS - 3

ER -