Surface effects at polymeric interfaces in capillary driving process

Ilenia Viola; Anna Zocco; Alessandra Fischetti; Barbara Foglieni; Laura Cremonesi; Maurizio Ferrari; Roberto Cingolani; Giuseppe Gigli

doi:10.1117/12.608302

Surface effects at polymeric interfaces in capillary driving process

Ilenia Viola, Anna Zocco, Alessandra Fischetti, Barbara Foglieni, Laura Cremonesi, Maurizio Ferrari, Roberto Cingolani, Giuseppe Gigli

IRCCS Ospedale San Raffaele

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The growing interest in biological micro-array and Lab-on-Chip (LOC) is justified by the possibility of reducing the sample volume, processing time and costs. By means microfluidics seems to be the prevalent tool for the integration of manifold processes in miniaturized devices. Anyway at a submillimeter scale the liquid behavior is affected by geometric confinement and wetting properties. In order to confine the liquid sample inside the LOC buried channels we have performed the sealing by poly(dimethylsiloxane) (PDMS), a silicon-based bi-component elastomer. The filling dynamics changes at changing of the polymer mixing ratio of the pre-polymer and the curing agent. In fact, a different concentration of cross-linker modifies the elastic, adhesion and wettability properties of the cover-slip.

Original language	English
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Editors	C. Cane, J.-C. Chiao, F.V. Verdu
Pages	389-398
Number of pages	10
Volume	5836
DOIs	https://doi.org/10.1117/12.608302
Publication status	Published - 2005
Event	Smart Sensors, Actuators, and MEMS II - Seville, Spain Duration: May 9 2005 → May 11 2005

Other

Other	Smart Sensors, Actuators, and MEMS II
Country/Territory	Spain
City	Seville
Period	5/9/05 → 5/11/05

Keywords

Confined geometry
DNA-chip
Liquid displacement
PDMS
Wetting properties

ASJC Scopus subject areas

Electrical and Electronic Engineering
Condensed Matter Physics

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10.1117/12.608302

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Surface effects at polymeric interfaces in capillary driving process. / Viola, Ilenia; Zocco, Anna; Fischetti, Alessandra; Foglieni, Barbara; Cremonesi, Laura; Ferrari, Maurizio; Cingolani, Roberto; Gigli, Giuseppe.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / C. Cane; J.-C. Chiao; F.V. Verdu. Vol. 5836 2005. p. 389-398 89.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Viola, I, Zocco, A, Fischetti, A, Foglieni, B, Cremonesi, L, Ferrari, M, Cingolani, R & Gigli, G 2005, Surface effects at polymeric interfaces in capillary driving process. in C Cane, J-C Chiao & FV Verdu (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5836, 89, pp. 389-398, Smart Sensors, Actuators, and MEMS II, Seville, Spain, 5/9/05. https://doi.org/10.1117/12.608302

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AU - Ferrari, Maurizio

AU - Cingolani, Roberto

AU - Gigli, Giuseppe

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AB - The growing interest in biological micro-array and Lab-on-Chip (LOC) is justified by the possibility of reducing the sample volume, processing time and costs. By means microfluidics seems to be the prevalent tool for the integration of manifold processes in miniaturized devices. Anyway at a submillimeter scale the liquid behavior is affected by geometric confinement and wetting properties. In order to confine the liquid sample inside the LOC buried channels we have performed the sealing by poly(dimethylsiloxane) (PDMS), a silicon-based bi-component elastomer. The filling dynamics changes at changing of the polymer mixing ratio of the pre-polymer and the curing agent. In fact, a different concentration of cross-linker modifies the elastic, adhesion and wettability properties of the cover-slip.

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KW - DNA-chip

KW - Liquid displacement

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KW - Wetting properties

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Surface effects at polymeric interfaces in capillary driving process

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Keywords

ASJC Scopus subject areas

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