PROPRIETA TENSIOATTIVE DELLA MUCOSA DELLA TUBA DI EUSTACHIO. POSSIBILI CORRELAZIONI CON IL SURFATTANTE ALVEOLARE

Translated title of the contribution: Surface tension lowering substance of the Eustachian tube. Possible correlations with the alveolar surfactant

E. Mira, P. Galioto, G. Zavattini

Research output: Contribution to journalArticle

Abstract

It has been shown experimentally that washings of the Eustachian tubes of several mammals (dog, guinea pig, rabbit) have surfactant properties. It is not known whether these properties are due to the presence of a specific phospholipid surfactant, analogous to that produced by alveolar pneumocytes, or are simply due to glycoprotein constituents of the mucosal layer of the Eustachian tube. Whichever is true, the tubal surfactant should act like pulmonary surfactant to render the tubal surface water-repellent and impede adhesion of two opposed surfaces. Changes in its composition could be important in the pathogenesis of seromucous otitis and drugs stimulating the production of surfactant should be effective for prevention or treatment of this disease.

Original languageItalian
Pages (from-to)349-353
Number of pages5
JournalRivista Italiana di Otorinolaringologia Audiologia e Foniatria
Volume5
Issue number3
Publication statusPublished - 1985

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Eustachian Tube
Surface Tension
Surface-Active Agents
Alveolar Epithelial Cells
Orosomucoid
Pulmonary Surfactants
Otitis
Mammals
Phospholipids
Glycoproteins
Guinea Pigs
Dogs
Rabbits
Water
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

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abstract = "It has been shown experimentally that washings of the Eustachian tubes of several mammals (dog, guinea pig, rabbit) have surfactant properties. It is not known whether these properties are due to the presence of a specific phospholipid surfactant, analogous to that produced by alveolar pneumocytes, or are simply due to glycoprotein constituents of the mucosal layer of the Eustachian tube. Whichever is true, the tubal surfactant should act like pulmonary surfactant to render the tubal surface water-repellent and impede adhesion of two opposed surfaces. Changes in its composition could be important in the pathogenesis of seromucous otitis and drugs stimulating the production of surfactant should be effective for prevention or treatment of this disease.",
author = "E. Mira and P. Galioto and G. Zavattini",
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T1 - PROPRIETA TENSIOATTIVE DELLA MUCOSA DELLA TUBA DI EUSTACHIO. POSSIBILI CORRELAZIONI CON IL SURFATTANTE ALVEOLARE

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AU - Galioto, P.

AU - Zavattini, G.

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N2 - It has been shown experimentally that washings of the Eustachian tubes of several mammals (dog, guinea pig, rabbit) have surfactant properties. It is not known whether these properties are due to the presence of a specific phospholipid surfactant, analogous to that produced by alveolar pneumocytes, or are simply due to glycoprotein constituents of the mucosal layer of the Eustachian tube. Whichever is true, the tubal surfactant should act like pulmonary surfactant to render the tubal surface water-repellent and impede adhesion of two opposed surfaces. Changes in its composition could be important in the pathogenesis of seromucous otitis and drugs stimulating the production of surfactant should be effective for prevention or treatment of this disease.

AB - It has been shown experimentally that washings of the Eustachian tubes of several mammals (dog, guinea pig, rabbit) have surfactant properties. It is not known whether these properties are due to the presence of a specific phospholipid surfactant, analogous to that produced by alveolar pneumocytes, or are simply due to glycoprotein constituents of the mucosal layer of the Eustachian tube. Whichever is true, the tubal surfactant should act like pulmonary surfactant to render the tubal surface water-repellent and impede adhesion of two opposed surfaces. Changes in its composition could be important in the pathogenesis of seromucous otitis and drugs stimulating the production of surfactant should be effective for prevention or treatment of this disease.

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