It has been shown experimentally that washings of the Eustachian tubes of several mammals (dog, guinea pig, rabbit) have surfactant properties. It is not known whether these properties are due to the presence of a specific phospholipid surfactant, analogous to that produced by alveolar pneumocytes, or are simply due to glycoprotein constituents of the mucosal layer of the Eustachian tube. Whichever is true, the tubal surfactant should act like pulmonary surfactant to render the tubal surface water-repellent and impede adhesion of two opposed surfaces. Changes in its composition could be important in the pathogenesis of seromucous otitis and drugs stimulating the production of surfactant should be effective for prevention or treatment of this disease.
|Translated title of the contribution||Surface tension lowering substance of the Eustachian tube. Possible correlations with the alveolar surfactant|
|Number of pages||5|
|Journal||Rivista Italiana di Otorinolaringologia Audiologia e Foniatria|
|Publication status||Published - 1985|
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