Surgery after radiochemotherapy for stage III lung cancer: Postoperative complications and late results

L. Tavecchio, G. Ravasi, A. V. Bedini, A. Gramaglia, F. Milani

Research output: Contribution to journalArticle

Abstract

Fifty-seven stage III lung cancer patients underwent radiochemotherapy and subsequent surgery. Forty radical (R -), six non-radical, and eleven exploratory operations were performed. Pneumonia (five cases), pulmonary insufficiency (one case), bronchial fistula (one case) were the major, non- fatal complications. Four deaths due to adult respiratory distress syndrome (ARDS) or pulmonary embolism occurred. Sixty percent of the 10 patients who had no viable tumor at operation survived 3 years, as well as 41% of those who achieved a complete remission by resection and 11% of those with residual disease (R+) after operation. However, the 1- and 2-year survival rates were similar. The main pattern of failure in R- and R+ patients was extra- and intra-RT-field progression, respectively. A slightly higher rate of postoperative complications, with respect to current practice, was observed. However, data lead to argument on the improvement of locoregional control and long-term survival following radical surgery.

Original languageEnglish
Pages (from-to)2-6
Number of pages5
JournalJournal of Surgical Oncology
Volume56
Issue number1
Publication statusPublished - 1994

Keywords

  • combined treatments
  • modality of failure
  • post-treatment stage
  • survival

ASJC Scopus subject areas

  • Surgery
  • Oncology

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