Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient

Pasquale Capaccio, Francesco Ottaviani, Valeria Cuccarini, Mario Corbellino, Carlo Parravicini, Stefano Menzo, Antonio Schindler, Lorenzo Pignataro

Research output: Contribution to journalArticle

Abstract

Intranasal schneiderian exophytic squamous papillomatosis is rare and often secondary to human papilloma virus infection. Treatment usually consists of repeated surgical or endoscopic excisions due to recurrences. The use of intravenous or intralesional or topically applied cidofovir, a cytidine nucleotide analogue suppressing viral replication, alone or as adjuvant therapy has been proposed and described in the literature for the treatment of other human papillomavirus (HPV)-related lesions. We firstly describe a successful combined approach of surgery and topical cidofovir for recurrent nasal HPV-related exophytic squamous papillomatosis in a HIV-infected patient. As no untoward effects were encountered this therapeutical option should be considered in the management of recurrent nasal papillomatosis in HIV-infected patients.

Original languageEnglish
Pages (from-to)937-939
Number of pages3
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume266
Issue number6
DOIs
Publication statusPublished - Jun 2009

Fingerprint

Papilloma
Nose
HIV
Papillomaviridae
Cytidine
Virus Diseases
Therapeutics
Nucleotides
Recurrence
cidofovir

Keywords

  • Cidofovir
  • Hepatitis C
  • HIV
  • HPV
  • Nasal papilloma
  • Papillomatosis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient. / Capaccio, Pasquale; Ottaviani, Francesco; Cuccarini, Valeria; Corbellino, Mario; Parravicini, Carlo; Menzo, Stefano; Schindler, Antonio; Pignataro, Lorenzo.

In: European Archives of Oto-Rhino-Laryngology, Vol. 266, No. 6, 06.2009, p. 937-939.

Research output: Contribution to journalArticle

Capaccio, Pasquale ; Ottaviani, Francesco ; Cuccarini, Valeria ; Corbellino, Mario ; Parravicini, Carlo ; Menzo, Stefano ; Schindler, Antonio ; Pignataro, Lorenzo. / Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient. In: European Archives of Oto-Rhino-Laryngology. 2009 ; Vol. 266, No. 6. pp. 937-939.
@article{6a3208c5d5a745e18e21b85d0fc06c7e,
title = "Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient",
abstract = "Intranasal schneiderian exophytic squamous papillomatosis is rare and often secondary to human papilloma virus infection. Treatment usually consists of repeated surgical or endoscopic excisions due to recurrences. The use of intravenous or intralesional or topically applied cidofovir, a cytidine nucleotide analogue suppressing viral replication, alone or as adjuvant therapy has been proposed and described in the literature for the treatment of other human papillomavirus (HPV)-related lesions. We firstly describe a successful combined approach of surgery and topical cidofovir for recurrent nasal HPV-related exophytic squamous papillomatosis in a HIV-infected patient. As no untoward effects were encountered this therapeutical option should be considered in the management of recurrent nasal papillomatosis in HIV-infected patients.",
keywords = "Cidofovir, Hepatitis C, HIV, HPV, Nasal papilloma, Papillomatosis",
author = "Pasquale Capaccio and Francesco Ottaviani and Valeria Cuccarini and Mario Corbellino and Carlo Parravicini and Stefano Menzo and Antonio Schindler and Lorenzo Pignataro",
year = "2009",
month = "6",
doi = "10.1007/s00405-008-0769-7",
language = "English",
volume = "266",
pages = "937--939",
journal = "European Archives of Oto-Rhino-Laryngology",
issn = "0937-4477",
publisher = "Springer Verlag",
number = "6",

}

TY - JOUR

T1 - Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient

AU - Capaccio, Pasquale

AU - Ottaviani, Francesco

AU - Cuccarini, Valeria

AU - Corbellino, Mario

AU - Parravicini, Carlo

AU - Menzo, Stefano

AU - Schindler, Antonio

AU - Pignataro, Lorenzo

PY - 2009/6

Y1 - 2009/6

N2 - Intranasal schneiderian exophytic squamous papillomatosis is rare and often secondary to human papilloma virus infection. Treatment usually consists of repeated surgical or endoscopic excisions due to recurrences. The use of intravenous or intralesional or topically applied cidofovir, a cytidine nucleotide analogue suppressing viral replication, alone or as adjuvant therapy has been proposed and described in the literature for the treatment of other human papillomavirus (HPV)-related lesions. We firstly describe a successful combined approach of surgery and topical cidofovir for recurrent nasal HPV-related exophytic squamous papillomatosis in a HIV-infected patient. As no untoward effects were encountered this therapeutical option should be considered in the management of recurrent nasal papillomatosis in HIV-infected patients.

AB - Intranasal schneiderian exophytic squamous papillomatosis is rare and often secondary to human papilloma virus infection. Treatment usually consists of repeated surgical or endoscopic excisions due to recurrences. The use of intravenous or intralesional or topically applied cidofovir, a cytidine nucleotide analogue suppressing viral replication, alone or as adjuvant therapy has been proposed and described in the literature for the treatment of other human papillomavirus (HPV)-related lesions. We firstly describe a successful combined approach of surgery and topical cidofovir for recurrent nasal HPV-related exophytic squamous papillomatosis in a HIV-infected patient. As no untoward effects were encountered this therapeutical option should be considered in the management of recurrent nasal papillomatosis in HIV-infected patients.

KW - Cidofovir

KW - Hepatitis C

KW - HIV

KW - HPV

KW - Nasal papilloma

KW - Papillomatosis

UR - http://www.scopus.com/inward/record.url?scp=67349132905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67349132905&partnerID=8YFLogxK

U2 - 10.1007/s00405-008-0769-7

DO - 10.1007/s00405-008-0769-7

M3 - Article

C2 - 18648834

AN - SCOPUS:67349132905

VL - 266

SP - 937

EP - 939

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

SN - 0937-4477

IS - 6

ER -