Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role

Antonio Chiappa; Emilio Bertani; Andrew P. Zbar; Roberto Biffi; Francesca Biella; Massimo Bellomi; Giulia Zampino; Nicola Fazio; Davide Poldi; Ugo Page; Bruno Andreoni

Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role

Antonio Chiappa, Emilio Bertani, Andrew P. Zbar, Roberto Biffi, Francesca Biella, Massimo Bellomi, Giulia Zampino, Nicola Fazio, Davide Poldi, Ugo Page, Bruno Andreoni

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article

Abstract

Background/Aims: To compare the short- and long-term outcome of older and younger patients with advanced colorectal cancer who underwent elective surgery. Methodology: Six hundred and ninety-two patients were analyzed. Four hundred and seventy-nine patients were 70 years (group 2). Results: The overall peroperative mortality rate in younger patients was 0.8% (n=7), and 1.4% (n=3) in the elderly (p=NS); morbidity was 35% and 42%, respectively (p=NS). On univariate analysis, elderly patients had a worse overall survival (OS) compared to younger, when only patients undergoing postoperative chemo-radiotherapy were considered (54% OS vs. 67% OS at 5 years; p=0.03). Using logistic regression analysis, tumor stage (p<0.0001) and radicality of surgery (p

Original language	English
Pages (from-to)	740-745
Number of pages	6
Journal	Hepato-Gastroenterology
Volume	54
Issue number	75
Publication status	Published - Apr 2007

Keywords

Chemotherapy
Elderly
Postoperative mortality
Radiotherapy
Risk factors
Survival

ASJC Scopus subject areas

Gastroenterology

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Chiappa, A., Bertani, E., Zbar, A. P., Biffi, R., Biella, F., Bellomi, M., Zampino, G., Fazio, N., Poldi, D., Page, U., & Andreoni, B. (2007). Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role. Hepato-Gastroenterology, 54(75), 740-745.

Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role. / Chiappa, Antonio ; Bertani, Emilio; Zbar, Andrew P.; Biffi, Roberto; Biella, Francesca; Bellomi, Massimo ; Zampino, Giulia ; Fazio, Nicola; Poldi, Davide; Page, Ugo; Andreoni, Bruno.

In: Hepato-Gastroenterology, Vol. 54, No. 75, 04.2007, p. 740-745.

Research output: Contribution to journal › Article

Chiappa, Antonio ; Bertani, Emilio ; Zbar, Andrew P. ; Biffi, Roberto ; Biella, Francesca ; Bellomi, Massimo ; Zampino, Giulia ; Fazio, Nicola ; Poldi, Davide ; Page, Ugo ; Andreoni, Bruno. / Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role. In: Hepato-Gastroenterology. 2007 ; Vol. 54, No. 75. pp. 740-745.

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