Surgery for advanced colorectal cancer in elderly patients with special emphasis for radio-chemotherapy role

Antonio Chiappa, Emilio Bertani, Andrew P. Zbar, Roberto Biffi, Francesca Biella, Massimo Bellomi, Giulia Zampino, Nicola Fazio, Davide Poldi, Ugo Page, Bruno Andreoni

Research output: Contribution to journalArticle

Abstract

Background/Aims: To compare the short- and long-term outcome of older and younger patients with advanced colorectal cancer who underwent elective surgery. Methodology: Six hundred and ninety-two patients were analyzed. Four hundred and seventy-nine patients were 70 years (group 2). Results: The overall peroperative mortality rate in younger patients was 0.8% (n=7), and 1.4% (n=3) in the elderly (p=NS); morbidity was 35% and 42%, respectively (p=NS). On univariate analysis, elderly patients had a worse overall survival (OS) compared to younger, when only patients undergoing postoperative chemo-radiotherapy were considered (54% OS vs. 67% OS at 5 years; p=0.03). Using logistic regression analysis, tumor stage (p<0.0001) and radicality of surgery (p

Original languageEnglish
Pages (from-to)740-745
Number of pages6
JournalHepato-Gastroenterology
Volume54
Issue number75
Publication statusPublished - Apr 2007

Keywords

  • Chemotherapy
  • Elderly
  • Postoperative mortality
  • Radiotherapy
  • Risk factors
  • Survival

ASJC Scopus subject areas

  • Gastroenterology

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