Surgery for esophageal carcinoma and the role of neoadjuvant therapy

Luigi Bonavina, Davide Bona, Alberto Luporini, Nicoletta Navoni, Roberto Zucali

Research output: Contribution to journalArticlepeer-review


Esophagectomy is a major surgical procedure. Due to the related morbidity and mortality, this operation should be carried out in high-volume referral centers by expert surgeons. Only patients in whom a complete resection is predictable at preoperative staging can consistently benefit from the operation. Chemoradiation therapy should be the first-line approach in patients with locally advanced tumors. A pathological complete response to neoadjuvant therapy is associated with a significantly improved long-term survival.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalActa Biomedica
Issue numberSUPPL. 2
Publication statusPublished - 2003


  • Esophagectomy
  • Esophagus
  • Lymphadenectomy
  • Neoadjuvant chemoradiation therapy

ASJC Scopus subject areas

  • Medicine(all)


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