Surgical experience with 168 primary liver cell carcinomas treated with hepatic resection

G. Gozzetti, A. Mazziotti, G. L. Grazi, E. Jovine, A. Gallucci, M. Morganti, A. Frena, V. Aguero, A. Cavallari

Research output: Contribution to journalArticlepeer-review


Liver resections were performed in 168 patients with hepatocellular carcinoma (HCC) over the past 10 years; 116 were cirrhotics. Operative mortality was 7.7% (8.6% in the cirrhotic group and 5.8% in non-cirrhotics). In the years 1987-1992 the operative mortality decreased from 15.6% to 4.9% (P <.05). A statistical analysis of survival was made with the data of 155 patients with a follow-up of more than 1 month after curative resection: 56 (36.1%) died, while 99 (63.8%) are currently alive, with a follow-up varying from 2 to 76 months. The actuarial survival rate is 56.7% after 3 years and 36.3% after 5 years (59% and 35.2% for cirrhotics; 52.2% and 37.7% for non- cirrhotics, respectively). Satisfactory results can be obtained after liver resections in HCC, even in the presence of cirrhosis. Further efforts are needed in the early diagnosis of HCC, to prevent the formation of satellite nodules and the intrahepatic tumoral spread, which represent the major cause of exclusion from surgical therapy.

Original languageEnglish
Pages (from-to)59-61
Number of pages3
JournalJournal of Surgical Oncology
Issue numberSUPPL. 3
Publication statusPublished - 1993


  • hepatocellular carcinoma
  • liver cirrhosis- surgery
  • liver cirrhosis-complications
  • liver neoplasms-surgery

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Surgery


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