Surgical management of cavernous angiomas in children

Marco Giulioni, Nicola Acciarri, Roberto Padovani, Franco Frank, Ercole Galassi, Giulio Gaist

Research output: Contribution to journalArticle

Abstract

Cavernous angiomas are vascular malformations affecting any part of the central nervous system (CNS). The management of asymptomatic cavernous angiomas is still debated due to their poorly understood natural history, although more data are now available regarding results of surgical treatment in symptomatic cases. The authors report their surgical experience with 18 pediatric patients operated on for symptomatic CNS cavernous angiomas. The children ranged in age from 10 months to 17 years, without a relevant sex difference. Cavernous angiomas were intracranial in 17 cases: 15 being in the supratentorial compartments and two in the cerebellum. Clinical manifestations were as follows: seizures in 11 cases, focal neurologic deficits in five, and headache in one. The 18th case was observed in a girl showing paraparesis in the spinal subdural-extramedullary space at T8-T9 level. Excision of four deep cerebral lesions was performed after stereotactic localization through non-eloquent cortex. Pathologic confirmation of cavernous angiomas was obtained in all patients. Mortality from surgical procedures was absent in this series. The follow-up period ranged from 1 to 16 years. All 11 epileptic patients obtained seizure control; improvement or stabilization of neurologic symptoms was observed in the remaining seven patients.

Original languageEnglish
Pages (from-to)194-199
Number of pages6
JournalSurgical Neurology
Volume42
Issue number3
DOIs
Publication statusPublished - 1994

Fingerprint

Cavernous Hemangioma
Neurologic Manifestations
Seizures
Central Nervous System Cavernous Hemangioma
Subdural Space
Paraparesis
Vascular Malformations
Natural History
Sex Characteristics
Cerebellum
Headache
Central Nervous System
Pediatrics
Mortality
Therapeutics

Keywords

  • Cavernous angioma
  • Epilepsy
  • Surgical treatment
  • Vascular malformation

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Giulioni, M., Acciarri, N., Padovani, R., Frank, F., Galassi, E., & Gaist, G. (1994). Surgical management of cavernous angiomas in children. Surgical Neurology, 42(3), 194-199. https://doi.org/10.1016/0090-3019(94)90262-3

Surgical management of cavernous angiomas in children. / Giulioni, Marco; Acciarri, Nicola; Padovani, Roberto; Frank, Franco; Galassi, Ercole; Gaist, Giulio.

In: Surgical Neurology, Vol. 42, No. 3, 1994, p. 194-199.

Research output: Contribution to journalArticle

Giulioni, M, Acciarri, N, Padovani, R, Frank, F, Galassi, E & Gaist, G 1994, 'Surgical management of cavernous angiomas in children', Surgical Neurology, vol. 42, no. 3, pp. 194-199. https://doi.org/10.1016/0090-3019(94)90262-3
Giulioni M, Acciarri N, Padovani R, Frank F, Galassi E, Gaist G. Surgical management of cavernous angiomas in children. Surgical Neurology. 1994;42(3):194-199. https://doi.org/10.1016/0090-3019(94)90262-3
Giulioni, Marco ; Acciarri, Nicola ; Padovani, Roberto ; Frank, Franco ; Galassi, Ercole ; Gaist, Giulio. / Surgical management of cavernous angiomas in children. In: Surgical Neurology. 1994 ; Vol. 42, No. 3. pp. 194-199.
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