Surgical management of early cervical cancer: The shape of future studies

Research output: Contribution to journalArticlepeer-review

Abstract

Early cervical cancer, in particular in the presence of favorable pathologic risk factors, accounts for a very low incidence of parametrial involvement and lymph node metastasis. This means that a less radical surgery may be an oncologically safe treatment in selected cases, with the aim of preserving fertility and/or reducing morbidity without compromising survival. The extensiveness of surgery has decreased relatively in recent decades, the "modified" radical hysterectomy still being the current gold standard by most international guidelines. Vaginal (or abdominal) radical trachelectomy, simple hysterectomy, or cervical conization has been proposed in association with pelvic lymphadenectomy. Sentinel lymph node mapping may be an option to avoid a complete pelvic lymphadenectomy. Ongoing research efforts are especially being made in properly identifying the patient subset suitable for a conservative/less radical approach and prospectively confirming the oncological safety of the proposed clinical-pathological algorithms.

Original languageEnglish
Pages (from-to)527-534
Number of pages8
JournalCurrent Oncology Reports
Volume14
Issue number6
DOIs
Publication statusPublished - Dec 2012

Keywords

  • Cervical conization
  • Conservative treatment
  • Early cervical cancer
  • Microinvasive cervical cancer
  • Radical hysterectomy
  • Radical trachelectomy
  • Sentinel lymph node
  • Surgical management

ASJC Scopus subject areas

  • Oncology

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