Abstract
This paper reports findings of the "Focus on Controversial Areas" Working Party of the Italian Senonetwork, which was set up to improve the care of breast cancer patients. After reviewing articles in English on the MEDLINE system on breast conserving surgery for invasive carcinoma, the Working Party presents their recommendations for identifying risk factors for positive margins, suggests how to manage them so as to achieve the highest possible percentage of negative margins, and proposes standards for investigating resection margins and therapeutic approaches according to margin status. When margins are positive, approaches include re-excision, mastectomy, or, as second-line treatment, radiotherapy with a high boost dose. When margins are negative, boost administration and its dose depend on the risk of local recurrence, which is linked to biopathological tumor features and surgical margin width. Although margin status does not affect the choice of systemic therapy, it may delay the start of chemotherapy when further surgery is required.
| Original language | English |
|---|---|
| Pages (from-to) | 284-289 |
| Number of pages | 6 |
| Journal | Tumori |
| Volume | 102 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1 2016 |
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Keywords
- Breast cancer
- Breast network
- Conservative surgery
- Surgical margin
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Surgical resection margins after breast-conserving surgery : Senonetwork recommendations. / Galimberti, Viviana; Taffurelli, Mario; Leonardi, Maria Cristina; Aristei, Cynthia; Trentin, Chiara; Cassano, Enrico; Pietribiasi, Francesca; Corso, Giovanni; Munzone, Elisabetta; Tondini, Carlo; Frigeri, Alfonso; Cataliotti, Luigi; Santini, Donatella.
In: Tumori, Vol. 102, No. 3, 01.05.2016, p. 284-289.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surgical resection margins after breast-conserving surgery
T2 - Senonetwork recommendations
AU - Galimberti, Viviana
AU - Taffurelli, Mario
AU - Leonardi, Maria Cristina
AU - Aristei, Cynthia
AU - Trentin, Chiara
AU - Cassano, Enrico
AU - Pietribiasi, Francesca
AU - Corso, Giovanni
AU - Munzone, Elisabetta
AU - Tondini, Carlo
AU - Frigeri, Alfonso
AU - Cataliotti, Luigi
AU - Santini, Donatella
PY - 2016/5/1
Y1 - 2016/5/1
N2 - This paper reports findings of the "Focus on Controversial Areas" Working Party of the Italian Senonetwork, which was set up to improve the care of breast cancer patients. After reviewing articles in English on the MEDLINE system on breast conserving surgery for invasive carcinoma, the Working Party presents their recommendations for identifying risk factors for positive margins, suggests how to manage them so as to achieve the highest possible percentage of negative margins, and proposes standards for investigating resection margins and therapeutic approaches according to margin status. When margins are positive, approaches include re-excision, mastectomy, or, as second-line treatment, radiotherapy with a high boost dose. When margins are negative, boost administration and its dose depend on the risk of local recurrence, which is linked to biopathological tumor features and surgical margin width. Although margin status does not affect the choice of systemic therapy, it may delay the start of chemotherapy when further surgery is required.
AB - This paper reports findings of the "Focus on Controversial Areas" Working Party of the Italian Senonetwork, which was set up to improve the care of breast cancer patients. After reviewing articles in English on the MEDLINE system on breast conserving surgery for invasive carcinoma, the Working Party presents their recommendations for identifying risk factors for positive margins, suggests how to manage them so as to achieve the highest possible percentage of negative margins, and proposes standards for investigating resection margins and therapeutic approaches according to margin status. When margins are positive, approaches include re-excision, mastectomy, or, as second-line treatment, radiotherapy with a high boost dose. When margins are negative, boost administration and its dose depend on the risk of local recurrence, which is linked to biopathological tumor features and surgical margin width. Although margin status does not affect the choice of systemic therapy, it may delay the start of chemotherapy when further surgery is required.
KW - Breast cancer
KW - Breast network
KW - Conservative surgery
KW - Surgical margin
UR - http://www.scopus.com/inward/record.url?scp=84977601526&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84977601526&partnerID=8YFLogxK
U2 - 10.5301/tj.5000500
DO - 10.5301/tj.5000500
M3 - Article
AN - SCOPUS:84977601526
VL - 102
SP - 284
EP - 289
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 3
ER -