Intervento di rivascolarizzazione degli arti inferiori mediante protesi in carbonio. Risultati a breve e medio termine

Translated title of the contribution: Surgical revascularization of the lower extremities using carbon grafts. Immediate and medium-term results

L. Dordoni, R. Chiesa, G. Melissano

Research output: Contribution to journalArticle

Abstract

Aims. This prospective, non-randomised study is designed to assess the short and medium-term results of using Carbograft® carbon-coated polyester vascular prostheses in the surgical revascularisation of the lower extremities. Methods. Between January 1997 and September 1998 60 patients (43 male, 15 female, mean age 68.2 years) were monitored after femoro-popliteal bypass procedures using Carbograft® prostheses. The indication to surgery was invalidating claudication in 65% and critical ischaemia in 35% of cases. All patients were subjected to preoperative angiography which revealed optimum run-off in 11 cases (18.3%), good run-off in 4 (68.4%) and minimal run-off in 8 (13.3%). A supragenicular femoropopliteal bypass operation was therefore performed on 49 patients (81.7%) and a subgenicular procedure on 11 (18.3%). Results. Mean follow-up lasted 314±207 days. Early complications (medium 30 days) included 5 cases of graft thrombosis (8.5%) requiring surgery and 1 case (1.7%) of aseptic periprosthetic effusion around the graft. Tardive complications included 8 cases (13.1 pt/yr) of graft thrombosis caused by stenosis of distal anastomosis and treated by PTA and 2 cases (3.3% pt/yr) of graft infection. There were no perioperative deaths. The probability of primary patency at one year was assessed using the Kaplan- Meier method and came to 70.0±7.1% (67.9±8.3% for supragenicular bypass cases and 80.2±12.6% for subgenicular procedures). The secondary patency figure was 88.8±4.4%. A statistically significant difference was noted in primary patency between patients with good/excellent and patients with poor run-off: the primary patency rates were 76.1±7.3% and 35.7±17.5%, respectively. Conclusions. The satisfactory results achieved in this series justify future randomised clinical studies designed to confirm the long-term advantages of using Carbograft® prostheses in infra-inguinal revascularisation procedures.

Original languageItalian
Pages (from-to)13-23
Number of pages11
JournalGiornale Italiano di Chirurgia Vascolare
Volume7
Issue number1
Publication statusPublished - 2000

Fingerprint

Lower Extremity
Carbon
Transplants
Prostheses and Implants
Thrombosis
Blood Vessel Prosthesis
Polyesters
Groin
Angiography
Pathologic Constriction
Ischemia
Infection

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

@article{09fef60195054a95b9d6b0382fa963bc,
title = "Intervento di rivascolarizzazione degli arti inferiori mediante protesi in carbonio. Risultati a breve e medio termine",
abstract = "Aims. This prospective, non-randomised study is designed to assess the short and medium-term results of using Carbograft{\circledR} carbon-coated polyester vascular prostheses in the surgical revascularisation of the lower extremities. Methods. Between January 1997 and September 1998 60 patients (43 male, 15 female, mean age 68.2 years) were monitored after femoro-popliteal bypass procedures using Carbograft{\circledR} prostheses. The indication to surgery was invalidating claudication in 65{\%} and critical ischaemia in 35{\%} of cases. All patients were subjected to preoperative angiography which revealed optimum run-off in 11 cases (18.3{\%}), good run-off in 4 (68.4{\%}) and minimal run-off in 8 (13.3{\%}). A supragenicular femoropopliteal bypass operation was therefore performed on 49 patients (81.7{\%}) and a subgenicular procedure on 11 (18.3{\%}). Results. Mean follow-up lasted 314±207 days. Early complications (medium 30 days) included 5 cases of graft thrombosis (8.5{\%}) requiring surgery and 1 case (1.7{\%}) of aseptic periprosthetic effusion around the graft. Tardive complications included 8 cases (13.1 pt/yr) of graft thrombosis caused by stenosis of distal anastomosis and treated by PTA and 2 cases (3.3{\%} pt/yr) of graft infection. There were no perioperative deaths. The probability of primary patency at one year was assessed using the Kaplan- Meier method and came to 70.0±7.1{\%} (67.9±8.3{\%} for supragenicular bypass cases and 80.2±12.6{\%} for subgenicular procedures). The secondary patency figure was 88.8±4.4{\%}. A statistically significant difference was noted in primary patency between patients with good/excellent and patients with poor run-off: the primary patency rates were 76.1±7.3{\%} and 35.7±17.5{\%}, respectively. Conclusions. The satisfactory results achieved in this series justify future randomised clinical studies designed to confirm the long-term advantages of using Carbograft{\circledR} prostheses in infra-inguinal revascularisation procedures.",
keywords = "Blood vessel prosthesis, Femoral artery surgery, Ischemia surgery, Leg blood supply, Popliteal artery surgery",
author = "L. Dordoni and R. Chiesa and G. Melissano",
year = "2000",
language = "Italian",
volume = "7",
pages = "13--23",
journal = "Giornale Italiano di Chirurgia Vascolare",
issn = "1122-8679",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "1",

}

TY - JOUR

T1 - Intervento di rivascolarizzazione degli arti inferiori mediante protesi in carbonio. Risultati a breve e medio termine

AU - Dordoni, L.

AU - Chiesa, R.

AU - Melissano, G.

PY - 2000

Y1 - 2000

N2 - Aims. This prospective, non-randomised study is designed to assess the short and medium-term results of using Carbograft® carbon-coated polyester vascular prostheses in the surgical revascularisation of the lower extremities. Methods. Between January 1997 and September 1998 60 patients (43 male, 15 female, mean age 68.2 years) were monitored after femoro-popliteal bypass procedures using Carbograft® prostheses. The indication to surgery was invalidating claudication in 65% and critical ischaemia in 35% of cases. All patients were subjected to preoperative angiography which revealed optimum run-off in 11 cases (18.3%), good run-off in 4 (68.4%) and minimal run-off in 8 (13.3%). A supragenicular femoropopliteal bypass operation was therefore performed on 49 patients (81.7%) and a subgenicular procedure on 11 (18.3%). Results. Mean follow-up lasted 314±207 days. Early complications (medium 30 days) included 5 cases of graft thrombosis (8.5%) requiring surgery and 1 case (1.7%) of aseptic periprosthetic effusion around the graft. Tardive complications included 8 cases (13.1 pt/yr) of graft thrombosis caused by stenosis of distal anastomosis and treated by PTA and 2 cases (3.3% pt/yr) of graft infection. There were no perioperative deaths. The probability of primary patency at one year was assessed using the Kaplan- Meier method and came to 70.0±7.1% (67.9±8.3% for supragenicular bypass cases and 80.2±12.6% for subgenicular procedures). The secondary patency figure was 88.8±4.4%. A statistically significant difference was noted in primary patency between patients with good/excellent and patients with poor run-off: the primary patency rates were 76.1±7.3% and 35.7±17.5%, respectively. Conclusions. The satisfactory results achieved in this series justify future randomised clinical studies designed to confirm the long-term advantages of using Carbograft® prostheses in infra-inguinal revascularisation procedures.

AB - Aims. This prospective, non-randomised study is designed to assess the short and medium-term results of using Carbograft® carbon-coated polyester vascular prostheses in the surgical revascularisation of the lower extremities. Methods. Between January 1997 and September 1998 60 patients (43 male, 15 female, mean age 68.2 years) were monitored after femoro-popliteal bypass procedures using Carbograft® prostheses. The indication to surgery was invalidating claudication in 65% and critical ischaemia in 35% of cases. All patients were subjected to preoperative angiography which revealed optimum run-off in 11 cases (18.3%), good run-off in 4 (68.4%) and minimal run-off in 8 (13.3%). A supragenicular femoropopliteal bypass operation was therefore performed on 49 patients (81.7%) and a subgenicular procedure on 11 (18.3%). Results. Mean follow-up lasted 314±207 days. Early complications (medium 30 days) included 5 cases of graft thrombosis (8.5%) requiring surgery and 1 case (1.7%) of aseptic periprosthetic effusion around the graft. Tardive complications included 8 cases (13.1 pt/yr) of graft thrombosis caused by stenosis of distal anastomosis and treated by PTA and 2 cases (3.3% pt/yr) of graft infection. There were no perioperative deaths. The probability of primary patency at one year was assessed using the Kaplan- Meier method and came to 70.0±7.1% (67.9±8.3% for supragenicular bypass cases and 80.2±12.6% for subgenicular procedures). The secondary patency figure was 88.8±4.4%. A statistically significant difference was noted in primary patency between patients with good/excellent and patients with poor run-off: the primary patency rates were 76.1±7.3% and 35.7±17.5%, respectively. Conclusions. The satisfactory results achieved in this series justify future randomised clinical studies designed to confirm the long-term advantages of using Carbograft® prostheses in infra-inguinal revascularisation procedures.

KW - Blood vessel prosthesis

KW - Femoral artery surgery

KW - Ischemia surgery

KW - Leg blood supply

KW - Popliteal artery surgery

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