Surgical therapy for undifferentiated (embryonal) sarcomas of the liver in adults

Gian Luca Grazi, Antonio Gallucci, Michele Masettl, Elio Jovine, Michelangelo Fiorentino, Alighieri Mazziotti, Giuseppe Gozzetti

Research output: Contribution to journalArticlepeer-review


Undifferentiated (embryonal) sarcoma of the liver is a rare malignant mesenchymal tumor with a poor prognosis. Thirty cases worldwide have been reported over the last 40 years. The absence of specific symptoms, the rapid tumor growth, the normality of the common tumoral markers and the consequential delay in the diagnosis, often allow a significant enlargement of the hepatic mass. Three patients ages 15, 25, and 60 were admitted to our department with such a tumor. In spite of the large dimensions of the neoplasms, all underwent a right hepatectomy without any major surgical complications. Two of them died due to tumor recurrence after 10 and 67 months, respectively. The one case remaining is alive and disease free 62 months postoperatively. The latter one was the only case where a complete tumoral capsule was found in the resected specimen. Surgery is strongly recommended for every case with evidence of a liver-confined tumor even if it is large.

Original languageEnglish
Pages (from-to)901-906
Number of pages6
JournalAmerican Surgeon
Issue number11
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Surgical therapy for undifferentiated (embryonal) sarcomas of the liver in adults'. Together they form a unique fingerprint.

Cite this