TERAPIA CHIRURGICA DELLE METASTASI EPATICHE DA TUMORE DEL COLON-RETTO. ANALISI DEI FATTORI PROGNOSTICI

Translated title of the contribution: Surgical treatment of colorectal cancer liver metastases. Analysis of prognostic factors

P. De Nardi, M. Stella, P. Gini, L. Galli, G. Ferrari, V. Di Carlo

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate clinical factors that may influence survival in patients with liver metastases of colorectal cancer, 58 patients who underwent curative resection between 1981 and 1991, were analyzed. There were 37 synchronous and 21 metachro nuous metastases, 35 solitary and 23 multiple, 11 unilobar and 12 bilobar. Surgical procedures involved anatomical resection in 24 patients and wedge resection in 34. Complications were observed in 18 patients (31%) with no postoperative mortality. Survival analysis was calculated with Kaplan Meier test and then compared with log-rank test. One, 3 and 5 year actuarial survival was 92%, 55% and 30%. Only 2 variables had a negative effect on survival: nonanatomical surgical procedure and synchronous diagnosis of metastases. Five-year survival was better for patients with anatomical (55.9%) than with wedge (21.1%) resection (p <0.02) and for patients with metachronous (46.6%) than with synchronous (0%) metastases (p <0.002). Resection of hepatic metastases from colorectal cancer seems to offer a reasonable chance of long term survival; anatomical resection should be preferred to wedge resection since it could offer better oncological results.

Translated title of the contributionSurgical treatment of colorectal cancer liver metastases. Analysis of prognostic factors
Original languageItalian
Pages (from-to)20-24
Number of pages5
JournalChirurgia
Volume9
Issue number1
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Surgery

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