Surgical treatment of early onset scoliosis in neurofibromatosis

Tiziana Greggi, Konstantinos Martikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Case series report of twenty-three patients, aged between 4 and 11 years, were surgically treated at the Authors' Spine Surgery Division in the past 15 years. Mean follow-up is 5 years (range, 18 months to 15 years). Mean age at the time of surgical procedure was 9.1 years (range, 4 years to 11 years). Average scoliosis was 48° (range, 38° to 82°) and skeletal maturity according to Risser sign was 0 in all of the patients. Patients were divided into 2 Groups according to the surgical procedure adopted. Posterior only instrumentation was performed in 16 patients that presented with a thoracic kyphosis lower than 50° (Group A), in the remaining 7 patients showing thoracic kyphosis exceeding 50°, combined anterior and posterior instrumented arthrodesis was performed (Group B). One patient, belonging to Group A, was instrumented with growing rod without fusion. Average correction of scoliosis was 60%, overall complication rate 24% and major 7%. Crankshaft phenomenon was observed in 21% (Group A): in these cases, anterior arthrodesis was performed after a mean 15-month from first surgical procedure. Fusion failure was observed in 1 (Group B) patient who underwent revision of posterior instrumentation. Clinical and radiographic evaluation at F-up showed good outcome in terms of deformity progression and quality of life. Early and aggressive surgery is the most effective management for dystrophic curves in neurofibromatosis has been proven to be. Our experience confirms the need for spinal stabilization even in pediatric age in rapidly progressive spinal deformities.

Original languageEnglish
Title of host publicationStudies in Health Technology and Informatics
Number of pages4
Publication statusPublished - 2012
Event9th Biennial Meeting of the International Research Society of Spinal Deformities, IRSSD 2012 - Poznan, Poland
Duration: Jul 1 2012Jul 4 2012


Other9th Biennial Meeting of the International Research Society of Spinal Deformities, IRSSD 2012


  • Early onset
  • Neurofibromatosis
  • NF1
  • Scoliosis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management


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