TY - JOUR
T1 - Surgical treatment of gastric adenocarcinoma
T2 - Impact on survival and quality of life. A prospective ten year study
AU - Braga, Marco
AU - Molinari, Michele
AU - Zuliani, Walter
AU - Foppa, Luciano
AU - Gianotti, Luca
AU - Radaelli, Giovanni
AU - Cristallo, Marco
AU - Di Carlo, Valerio
PY - 1996
Y1 - 1996
N2 - Background/Aims: The objective of this prospective study was to compare the results of total (TG) versus subtotal (SG) gastrectomy in patients with adenocarcinoma of the lower true-thirds of the stomach. Patients and Methods: Two hundred and twenty-seven patients underwent curative operation. Preoperative nutritional assessment, postoperative tumor stage, postoperative morbidity/mortality, five-year survival, postgastrectomy dietary intake and nutritional sequelae were recorded in all patients. Results: Postoperative mortality rate was 2.8% in the TG group and 1.1% in the SG group. The number of reoperations, anastomotic dehiscence rate and the length of postoperative stay were higher in the TG group. Five-year survival was closely related to lymph node involvement and gastric wall invasion. The extent of gastric resection did not influence survival when patients were matched for cancer stage. In the SG group, no recurrence in the gastric stump was observed. SG group showed a higher dietary energy intake than the TG group (p <0.01). This might explain the ability of the SG group to increase body weight more than. the TG group (p <0.01). Only the TG group needed a monthly parenteral vitamin B12 supplements starting 36 months after surgery. Conclusion: The results suggest that SG should be considered the treatment of choice of the gastric adenocarcinoma when a cancer-free proximal resection margin can be guaranteed.
AB - Background/Aims: The objective of this prospective study was to compare the results of total (TG) versus subtotal (SG) gastrectomy in patients with adenocarcinoma of the lower true-thirds of the stomach. Patients and Methods: Two hundred and twenty-seven patients underwent curative operation. Preoperative nutritional assessment, postoperative tumor stage, postoperative morbidity/mortality, five-year survival, postgastrectomy dietary intake and nutritional sequelae were recorded in all patients. Results: Postoperative mortality rate was 2.8% in the TG group and 1.1% in the SG group. The number of reoperations, anastomotic dehiscence rate and the length of postoperative stay were higher in the TG group. Five-year survival was closely related to lymph node involvement and gastric wall invasion. The extent of gastric resection did not influence survival when patients were matched for cancer stage. In the SG group, no recurrence in the gastric stump was observed. SG group showed a higher dietary energy intake than the TG group (p <0.01). This might explain the ability of the SG group to increase body weight more than. the TG group (p <0.01). Only the TG group needed a monthly parenteral vitamin B12 supplements starting 36 months after surgery. Conclusion: The results suggest that SG should be considered the treatment of choice of the gastric adenocarcinoma when a cancer-free proximal resection margin can be guaranteed.
KW - Anemia
KW - Gastrectomy
KW - Gastric adenocarcinoma
KW - Long-term survival
KW - Nutritional status
KW - Postoperative complications
UR - http://www.scopus.com/inward/record.url?scp=0029863195&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029863195&partnerID=8YFLogxK
M3 - Article
C2 - 8682460
AN - SCOPUS:0029863195
VL - 43
SP - 187
EP - 193
JO - Acta hepato-splenologica
JF - Acta hepato-splenologica
SN - 0172-6390
IS - 7
ER -