Surgical treatment of gastric cancer invading the oesophagus

F. Bozzetti, P. Bignami, L. Bertario, S. Fissi, M. Eboli

Research output: Contribution to journalArticlepeer-review


Introduction: There is controversy regarding which type of surgical treatment is most appropriate for upper gastric cancer invading the oesophagus. Methods: A review of the pertinent literature was carried out regarding oesophageal involvement in gastric cancer. Results: Invasion of the oesophagus occurred in 26-63% of Western surgical series. It was more frequent in Borrmann IV type, linitis plastica, pT3-pT4, diffuse type by Lauren, N+ or tumours exceeding 5 cm in diameter. Lymphatic tumuor spread was caudad (coeliac nodes, hepatoduodenal nodes, paraortic nodes) but mediastinal nodes were also involved if tumour growth in the oesophagus exceeded 3 cm or if there was transmural oesophageal infiltration. In Western countries there was less than 30% 5-year survival and no long-term survivors when hepatoduodenal or mediastinal nodes were metastatic. Mediastinal dissection through thoracotomy did not provide any benefit. Conclusions: A rational approach involves total gastrectomy plus partial oesophagectomy. Abdominal transhiatal resection may be performed in the case of a localized, non-infiltrating tumour and oesophageal involvement 3 cm, or hepatoduodenal or mediastinal nodes are positive, no surgical procedure is curative and the literature demonstrates that extended aggressive surgery has no benefits.

Original languageEnglish
Pages (from-to)810-814
Number of pages5
JournalEuropean Journal of Surgical Oncology
Issue number8
Publication statusPublished - 2000


  • Cancer of proximal stomach

ASJC Scopus subject areas

  • Oncology
  • Surgery

Fingerprint Dive into the research topics of 'Surgical treatment of gastric cancer invading the oesophagus'. Together they form a unique fingerprint.

Cite this