Surgical treatment of gastric cancer invading the oesophagus

F. Bozzetti, P. Bignami, L. Bertario, S. Fissi, M. Eboli

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Introduction: There is controversy regarding which type of surgical treatment is most appropriate for upper gastric cancer invading the oesophagus. Methods: A review of the pertinent literature was carried out regarding oesophageal involvement in gastric cancer. Results: Invasion of the oesophagus occurred in 26-63% of Western surgical series. It was more frequent in Borrmann IV type, linitis plastica, pT3-pT4, diffuse type by Lauren, N+ or tumours exceeding 5 cm in diameter. Lymphatic tumuor spread was caudad (coeliac nodes, hepatoduodenal nodes, paraortic nodes) but mediastinal nodes were also involved if tumour growth in the oesophagus exceeded 3 cm or if there was transmural oesophageal infiltration. In Western countries there was less than 30% 5-year survival and no long-term survivors when hepatoduodenal or mediastinal nodes were metastatic. Mediastinal dissection through thoracotomy did not provide any benefit. Conclusions: A rational approach involves total gastrectomy plus partial oesophagectomy. Abdominal transhiatal resection may be performed in the case of a localized, non-infiltrating tumour and oesophageal involvement 3 cm, or hepatoduodenal or mediastinal nodes are positive, no surgical procedure is curative and the literature demonstrates that extended aggressive surgery has no benefits.

Original languageEnglish
Pages (from-to)810-814
Number of pages5
JournalEuropean Journal of Surgical Oncology
Volume26
Issue number8
DOIs
Publication statusPublished - 2000

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Esophageal Neoplasms
Stomach Neoplasms
Esophagus
Linitis Plastica
Neoplasms
Esophagectomy
Thoracotomy
Gastrectomy
Abdomen
Survivors
Dissection
Therapeutics
Survival
Growth

Keywords

  • Cancer of proximal stomach

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Surgical treatment of gastric cancer invading the oesophagus. / Bozzetti, F.; Bignami, P.; Bertario, L.; Fissi, S.; Eboli, M.

In: European Journal of Surgical Oncology, Vol. 26, No. 8, 2000, p. 810-814.

Research output: Contribution to journalArticle

Bozzetti, F. ; Bignami, P. ; Bertario, L. ; Fissi, S. ; Eboli, M. / Surgical treatment of gastric cancer invading the oesophagus. In: European Journal of Surgical Oncology. 2000 ; Vol. 26, No. 8. pp. 810-814.
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