Surgical treatment of intestinal complications after radiotherapy and surgery for malignant lymphoma and carcinoma of the testis

L. Gennari, A. Balestrazzi, R. Zucali, G. Pizzocaro, F. Concolino, U. Veronesi

Research output: Contribution to journalArticle

Abstract

The aim of this paper is the analysis of the complications occurring after surgical and radiological procedures, for staging and treatment of malignant lymphomas and testicular carcinoma with an evaluation of the possible efficacy of their surgical treatment. During the period 1970-1976, 718 patients with malignant lymphomas were treated with laparosplenectomy; 444 of them received radiotherapy on the abdominal area. Laparosplenectomy was not performed on another 123 cases who were also irradiated on the abdominal area. Retroperitoneal lymphadenectomy or explorative laparotomy were carried out in 98 patients with carcinoma of the testis and 46 of them received adjuvant radiotherapy; another 29 were irradiated without previous surgical procedures. After surgery alone morbidity and mortality rate were 2.7% and 0.73% respectively. The mortality/morbidity ratio was 26%. The incidence of complications after radiotherapy alone was 3.3%. No deaths followed the treatment. Combined treatment had a morbidity rate of 5.5% and mortality rate of 2%. The mortality/morbidity ratio was 37%. Complications were treated mainly by surgery: out of 50 interventions, 22 were intestinal resections. New secondary complications were however frequent (more than 50% after intestinal resection) especially in patients originally treated with laparosplenectomy or retroperitoneal dissection plus radiotherapy.

Original languageEnglish
Pages (from-to)625-633
Number of pages9
JournalTumori
Volume65
Issue number5
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Cancer Research

Fingerprint Dive into the research topics of 'Surgical treatment of intestinal complications after radiotherapy and surgery for malignant lymphoma and carcinoma of the testis'. Together they form a unique fingerprint.

  • Cite this

    Gennari, L., Balestrazzi, A., Zucali, R., Pizzocaro, G., Concolino, F., & Veronesi, U. (1979). Surgical treatment of intestinal complications after radiotherapy and surgery for malignant lymphoma and carcinoma of the testis. Tumori, 65(5), 625-633.