Surgical treatment of pancreatic tumors in childhood and adolescence: Uncommon neoplasms with favorable outcome

Giovanni Marchegiani, Stefano Crippa, Giuseppe Malleo, Stefano Partelli, Paola Capelli, Paolo Pederzoli, Massimo Falconi

Research output: Contribution to journalArticlepeer-review


Background/Aims: Pancreatic tumors in children and adolescents are uncommon. The aim of the present paper was to analyze short- and long-term outcomes after surgical treatment of primary pancreatic neoplasms in children and adolescents at a single high-volume center for pancreatic diseases. Methods: Retrospective review of medical records and pathology reports of patients younger than 18 years who underwent surgery at Verona University Hospital from 1990 through 2010. Results: The study population consisted of 20 patients. Abdominal pain and palpable mass were the most common presenting symptoms. No patient had a locally advanced, unresectable or metastatic disease. Complete resection (R0) was achieved in 19 patients. There was no postoperative mortality, but postoperative complications occurred in 5 cases (25%). Histological examination showed 12 solid pseudopapillary tumors, 5 neuroendocrine tumors, 2 cystadenomas and 1 epithelial malignant tumor. At a median follow-up of 49.5 months (range: 7-234), there was no tumor recurrence. Postoperative diabetes was diagnosed in 1 patient and 4 other patients developed pancreatic exocrine insufficiency. Conclusion: In the setting of a high-volume surgical center, radical resection of pancreatic tumors in children and adolescents is associated with acceptable postoperative morbidity and favorable long-term outcome.

Original languageEnglish
Pages (from-to)383-389
Number of pages7
Issue number4
Publication statusPublished - Oct 2011


  • Adolescents
  • Children
  • Pancreatic tumors
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology


Dive into the research topics of 'Surgical treatment of pancreatic tumors in childhood and adolescence: Uncommon neoplasms with favorable outcome'. Together they form a unique fingerprint.

Cite this