Surgically treatable growth retardation due to non-neoplastic pituitary-hypothalamic dysfunction

C. DiRocco, A. Iannelli, P. Borrelli, M. Cappa, C. Colosimo

Research output: Contribution to journalArticlepeer-review


Out of 90 children, examined because of growth failure, 15 have been treated surgically. The diagnosis were intrasellar arachnoid diverticulum or empty sella (5 cases), enlarged chiasmatic cisterns (5 cases), chronic 'occult' hydrocephalus (5 cases). Surgery was followed by an immediate increase in growth rate in almost all the cases, even if the result was persistent only in some subjects. In percentage, better results were obtained in patients with enlarged chiasmatic cisterns and chronic occult hydrocephalus than in patients with arachnoid diverticulum or empty sella. The evaluation of prolactin serum levels was demonstrated to be usful both in preoperative diagnosis and postoperative control.

Original languageEnglish
Pages (from-to)353-368
Number of pages16
JournalChild's Brain
Issue number6
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology
  • Neuroscience(all)


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