Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste

Seven years' experience

P. D'Agaro, M. Andolina, P. Burgnich, E. Samar, C. Campello

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.

Original languageEnglish
Pages (from-to)54-57
Number of pages4
JournalHaematologica
Volume85
Issue number11 SUPPL.
Publication statusPublished - 2000

Fingerprint

Cytomegalovirus Infections
Bone Marrow
Transplants
Cytomegalovirus
Immunogenetics
Unrelated Donors
Incidence
Autografts
Graft vs Host Disease
Tissue Donors
Polymerase Chain Reaction

Keywords

  • Bone marrow transplant
  • Cytomegalovirus
  • PCR
  • Surveillance

ASJC Scopus subject areas

  • Hematology

Cite this

D'Agaro, P., Andolina, M., Burgnich, P., Samar, E., & Campello, C. (2000). Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste: Seven years' experience. Haematologica, 85(11 SUPPL.), 54-57.

Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste : Seven years' experience. / D'Agaro, P.; Andolina, M.; Burgnich, P.; Samar, E.; Campello, C.

In: Haematologica, Vol. 85, No. 11 SUPPL., 2000, p. 54-57.

Research output: Contribution to journalArticle

D'Agaro, P, Andolina, M, Burgnich, P, Samar, E & Campello, C 2000, 'Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste: Seven years' experience', Haematologica, vol. 85, no. 11 SUPPL., pp. 54-57.
D'Agaro P, Andolina M, Burgnich P, Samar E, Campello C. Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste: Seven years' experience. Haematologica. 2000;85(11 SUPPL.):54-57.
D'Agaro, P. ; Andolina, M. ; Burgnich, P. ; Samar, E. ; Campello, C. / Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste : Seven years' experience. In: Haematologica. 2000 ; Vol. 85, No. 11 SUPPL. pp. 54-57.
@article{5cd1e570444f493e828fd92c96449b28,
title = "Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste: Seven years' experience",
abstract = "Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8{\%} incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.",
keywords = "Bone marrow transplant, Cytomegalovirus, PCR, Surveillance",
author = "P. D'Agaro and M. Andolina and P. Burgnich and E. Samar and C. Campello",
year = "2000",
language = "English",
volume = "85",
pages = "54--57",
journal = "Haematologica",
issn = "0390-6078",
publisher = "NLM (Medline)",
number = "11 SUPPL.",

}

TY - JOUR

T1 - Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste

T2 - Seven years' experience

AU - D'Agaro, P.

AU - Andolina, M.

AU - Burgnich, P.

AU - Samar, E.

AU - Campello, C.

PY - 2000

Y1 - 2000

N2 - Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.

AB - Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.

KW - Bone marrow transplant

KW - Cytomegalovirus

KW - PCR

KW - Surveillance

UR - http://www.scopus.com/inward/record.url?scp=0033711151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033711151&partnerID=8YFLogxK

M3 - Article

VL - 85

SP - 54

EP - 57

JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 11 SUPPL.

ER -