Abstract
Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.
| Original language | English |
|---|---|
| Pages (from-to) | 54-57 |
| Number of pages | 4 |
| Journal | Haematologica |
| Volume | 85 |
| Issue number | 11 SUPPL. |
| Publication status | Published - 2000 |
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Keywords
- Bone marrow transplant
- Cytomegalovirus
- PCR
- Surveillance
ASJC Scopus subject areas
- Hematology
Cite this
Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste : Seven years' experience. / D'Agaro, P.; Andolina, M.; Burgnich, P.; Samar, E.; Campello, C.
In: Haematologica, Vol. 85, No. 11 SUPPL., 2000, p. 54-57.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surveillance of cytomegalovirus infections in bone marrow transplant in Trieste
T2 - Seven years' experience
AU - D'Agaro, P.
AU - Andolina, M.
AU - Burgnich, P.
AU - Samar, E.
AU - Campello, C.
PY - 2000
Y1 - 2000
N2 - Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.
AB - Forty-five consecutive patients submitted to a bone marrow transplant (BMT) were followed up weekly in order to evaluate the incidence of cytomegalovirus (CMV) infections on the basis of CMV antigenemia and polymerase chain reaction. All but one transplanted patients engrafted; fourteen patients out of these were CMV antigenemia positive after 16-184 days (median 32.5, mean 43.4) with an 31.8% incidence. CMV infections were associated with graft-versus-host disease and immunogenetic relationship between the donor and the recipient. No CMV infection was detectable in autologous transplants while antigenemia was demonstrated in 3/11 and 6/7 patients with BMT from respectively mismatched related and matched unrelated donors. (C) 2000, Ferrata Storti Foundation.
KW - Bone marrow transplant
KW - Cytomegalovirus
KW - PCR
KW - Surveillance
UR - http://www.scopus.com/inward/record.url?scp=0033711151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033711151&partnerID=8YFLogxK
M3 - Article
C2 - 11268325
AN - SCOPUS:0033711151
VL - 85
SP - 54
EP - 57
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 11 SUPPL.
ER -