Abstract
We evaluated the frequency of seroconversion for toxoplasmosis in seronegative recipients of thoracic solid organ transplants with seronegative or seropositive donors and the efficacy of chemoprophylaxis with pyrimethamine+sulfametopirazine. One hundred and sixty one patients seronegative for toxoplasmosis were followed-up at different intervals. Six patients out of 79 R-/D- and twelve out of 82 R-/D+ seroconverted after chemoprophylaxis interruption. There was no difference between matched and mismatched recipients as to the frequency of seroconversion which therefore could not be related to donor seropositivity. Seroconversions were almost asymptomatic. All positive recipients should be tested if symptoms of infection are present.
| Original language | English |
|---|---|
| Pages (from-to) | 299-302 |
| Number of pages | 4 |
| Journal | New Microbiologica |
| Volume | 30 |
| Issue number | 3 |
| Publication status | Published - Jul 2007 |
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Keywords
- Prophylaxis
- Thoracic solid organ transplantation
- Toxoplasmosis
ASJC Scopus subject areas
- Microbiology (medical)
- Microbiology
Cite this
Sarchi, E., Genco, F., Di Matteo, A., Castiglioni, B., Minoli, L., & Meroni, V. (2007). Surveillance of toxoplasma gondii infection in recipients of thoracic solid organ transplants. New Microbiologica, 30(3), 299-302.