Surveillance or lymph node dissection in clinical stage I non-seminomatous germinal testis cancer?

G. Pizzocaro, F. Zanoni, R. Salvioni, A. Milani, L. Piva

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Surveillance following orchiectomy alone has gained popularity in the management of clinical stage I non-seminomatous germ cell tumours (NSGCT) of the testis. However, long-term follow-up of the retroperitoneal nodes can be difficult. We analysed the results of 71 consecutive patients followed for more than 1 year. Fifty men (70.5%) remain disease-free and 21 (29.5%) have relapsed. Relapses occurred 2 to 36 months after orchiectomy (median 6 months). Retroperitoneal nodes were involved in 12 cases (17%). In only one patient were retroperitoneal metastases diagnosed when smaller than 2 cm and in four they were diagnosed when larger than 5 cm. Furthermore, the late relapses occurred in the retroperitoneal nodes. After treatment of metastases, 69 patients (97%) are alive, disease-free and off therapy. As retroperitoneal relapses do not occur after a properly executed retroperitoneal lymph node dissection (RPLND) and ejaculation problems can be avoided with unilateral RPLND, it is suggested that RPLND can be used for clinical stage I NSGCT of the testis in experienced surgical centres, with the advantage of an easier follow-up.

Original languageEnglish
Pages (from-to)759-762
Number of pages4
JournalBritish Journal of Urology
Volume57
Issue number6
Publication statusPublished - 1985

Fingerprint

Testicular Neoplasms
Lymph Node Excision
Orchiectomy
Recurrence
Testis
Neoplasm Metastasis
Ejaculation
Therapeutics
Nonseminomatous germ cell tumor

ASJC Scopus subject areas

  • Urology

Cite this

Surveillance or lymph node dissection in clinical stage I non-seminomatous germinal testis cancer? / Pizzocaro, G.; Zanoni, F.; Salvioni, R.; Milani, A.; Piva, L.

In: British Journal of Urology, Vol. 57, No. 6, 1985, p. 759-762.

Research output: Contribution to journalArticle

@article{820b866af8e641e0ae35ca8a35fde948,
title = "Surveillance or lymph node dissection in clinical stage I non-seminomatous germinal testis cancer?",
abstract = "Surveillance following orchiectomy alone has gained popularity in the management of clinical stage I non-seminomatous germ cell tumours (NSGCT) of the testis. However, long-term follow-up of the retroperitoneal nodes can be difficult. We analysed the results of 71 consecutive patients followed for more than 1 year. Fifty men (70.5{\%}) remain disease-free and 21 (29.5{\%}) have relapsed. Relapses occurred 2 to 36 months after orchiectomy (median 6 months). Retroperitoneal nodes were involved in 12 cases (17{\%}). In only one patient were retroperitoneal metastases diagnosed when smaller than 2 cm and in four they were diagnosed when larger than 5 cm. Furthermore, the late relapses occurred in the retroperitoneal nodes. After treatment of metastases, 69 patients (97{\%}) are alive, disease-free and off therapy. As retroperitoneal relapses do not occur after a properly executed retroperitoneal lymph node dissection (RPLND) and ejaculation problems can be avoided with unilateral RPLND, it is suggested that RPLND can be used for clinical stage I NSGCT of the testis in experienced surgical centres, with the advantage of an easier follow-up.",
author = "G. Pizzocaro and F. Zanoni and R. Salvioni and A. Milani and L. Piva",
year = "1985",
language = "English",
volume = "57",
pages = "759--762",
journal = "British Journal of Urology",
issn = "0007-1331",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Surveillance or lymph node dissection in clinical stage I non-seminomatous germinal testis cancer?

AU - Pizzocaro, G.

AU - Zanoni, F.

AU - Salvioni, R.

AU - Milani, A.

AU - Piva, L.

PY - 1985

Y1 - 1985

N2 - Surveillance following orchiectomy alone has gained popularity in the management of clinical stage I non-seminomatous germ cell tumours (NSGCT) of the testis. However, long-term follow-up of the retroperitoneal nodes can be difficult. We analysed the results of 71 consecutive patients followed for more than 1 year. Fifty men (70.5%) remain disease-free and 21 (29.5%) have relapsed. Relapses occurred 2 to 36 months after orchiectomy (median 6 months). Retroperitoneal nodes were involved in 12 cases (17%). In only one patient were retroperitoneal metastases diagnosed when smaller than 2 cm and in four they were diagnosed when larger than 5 cm. Furthermore, the late relapses occurred in the retroperitoneal nodes. After treatment of metastases, 69 patients (97%) are alive, disease-free and off therapy. As retroperitoneal relapses do not occur after a properly executed retroperitoneal lymph node dissection (RPLND) and ejaculation problems can be avoided with unilateral RPLND, it is suggested that RPLND can be used for clinical stage I NSGCT of the testis in experienced surgical centres, with the advantage of an easier follow-up.

AB - Surveillance following orchiectomy alone has gained popularity in the management of clinical stage I non-seminomatous germ cell tumours (NSGCT) of the testis. However, long-term follow-up of the retroperitoneal nodes can be difficult. We analysed the results of 71 consecutive patients followed for more than 1 year. Fifty men (70.5%) remain disease-free and 21 (29.5%) have relapsed. Relapses occurred 2 to 36 months after orchiectomy (median 6 months). Retroperitoneal nodes were involved in 12 cases (17%). In only one patient were retroperitoneal metastases diagnosed when smaller than 2 cm and in four they were diagnosed when larger than 5 cm. Furthermore, the late relapses occurred in the retroperitoneal nodes. After treatment of metastases, 69 patients (97%) are alive, disease-free and off therapy. As retroperitoneal relapses do not occur after a properly executed retroperitoneal lymph node dissection (RPLND) and ejaculation problems can be avoided with unilateral RPLND, it is suggested that RPLND can be used for clinical stage I NSGCT of the testis in experienced surgical centres, with the advantage of an easier follow-up.

UR - http://www.scopus.com/inward/record.url?scp=0022403917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022403917&partnerID=8YFLogxK

M3 - Article

VL - 57

SP - 759

EP - 762

JO - British Journal of Urology

JF - British Journal of Urology

SN - 0007-1331

IS - 6

ER -