Survival after AIDS diagnosis in Italy, 1999-2006: A population-based study

Diego Serraino, Antonella Zucchetto, Barbara Suligoi, Silvia Bruzzone, Laura Camoni, Stefano Boros, Angela De Paoli, Luigino Dal Maso, Silvia Franceschi, Giovanni Rezza

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To provide survival estimates of Italian people with AIDS (PWA) in the highly active antiretroviral therapy era and to identify prognostic factors at diagnosis and illnesses present at death. DESIGN: Longitudinal study with all-cause mortality as end point. METHODS: The vital status and illnesses present at death of the 9662 Italian PWA diagnosed from 1999 to 2005 were evaluated through a record linkage with the Italian mortality database. The survival was estimated through Kaplan-Meier method, whereas hazard ratios were computed to identify prognostic factors in the first 12 months or later. RESULTS: 80.6% of PWA survived 1 year, 75.2% 2 years, and 66.4% 5 years. Elevated death risks emerged among older individuals, injection drug users, and those with a CD4 cell count

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes
Volume52
Issue number1
DOIs
Publication statusPublished - Sep 2009

Keywords

  • AIDS-defining illnesses
  • Cancer
  • HAART
  • Italy
  • Non AIDS-defining deaths
  • Survival

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)

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    Serraino, D., Zucchetto, A., Suligoi, B., Bruzzone, S., Camoni, L., Boros, S., Paoli, A. D., Maso, L. D., Franceschi, S., & Rezza, G. (2009). Survival after AIDS diagnosis in Italy, 1999-2006: A population-based study. Journal of Acquired Immune Deficiency Syndromes, 52(1), 99-105. https://doi.org/10.1097/QAI.0b013e3181a4f663