Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014

Chiara Panato, Khaled Abusamaan, Ettore Bidoli, Mokhtar Hamdi-Cherif, Daniela Pierannunzio, Stefano Ferretti, Mahmoud Daher, Fouad Elissawi, Diego Serraino

Research output: Contribution to journalArticle

Abstract

Background: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival experience of people diagnosed with breast (BC) or colorectal (CRC) cancer from 2005 to 2014. Methods: Data included 1360 BC cases (median age 55.1 years) and 722 CRC cases (median age: 59.5 years; 52.5% men) recorded by the Gaza Cancer Registry according to a standard protocol. Clinical information was available for cases diagnosed in 2005-2006 only. Survival probabilities were estimated by Kaplan-Meyer method, while hazard ratios (HRs) and 95% confidence intervals (CI), adjusted for age and sex, were computed to assess factors associated with the risk of death. Results: Five-year survival was 65.1% for women with BC and 50.2% for patients with CRC. Advanced age (> 65 years), stage, and grade increased the death risk. Full access to therapies was associated with a reduced risk of death as compared with patients who had limited access (HR = 0.26, 95% CI:0.13-0.51 for BC; and HR = 0.11, 95% CI:0.04-0.31 for CRC). Conclusion(s): The 5-year survival after BC or CRC in the Gaza Strip was in line with estimates from surrounding Arab countries, but it was much lower than in developed Mediterranean countries (e.g., in Italy or in Jewish people in Israel).

Original languageEnglish
Article number632
JournalBMC Cancer
Volume18
Issue number1
DOIs
Publication statusPublished - Jun 4 2018

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Middle East
Colorectal Neoplasms
Breast Neoplasms
Survival
Confidence Intervals
Israel
Developed Countries
Italy
Registries
Neoplasms
Health
Therapeutics

Keywords

  • Breast cancer
  • Cancer survival
  • Colorectal cancer
  • Gaza Strip

ASJC Scopus subject areas

  • Oncology
  • Genetics
  • Cancer Research

Cite this

Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014. / Panato, Chiara; Abusamaan, Khaled; Bidoli, Ettore; Hamdi-Cherif, Mokhtar; Pierannunzio, Daniela; Ferretti, Stefano; Daher, Mahmoud; Elissawi, Fouad; Serraino, Diego.

In: BMC Cancer, Vol. 18, No. 1, 632, 04.06.2018.

Research output: Contribution to journalArticle

Panato, Chiara ; Abusamaan, Khaled ; Bidoli, Ettore ; Hamdi-Cherif, Mokhtar ; Pierannunzio, Daniela ; Ferretti, Stefano ; Daher, Mahmoud ; Elissawi, Fouad ; Serraino, Diego. / Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014. In: BMC Cancer. 2018 ; Vol. 18, No. 1.
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abstract = "Background: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival experience of people diagnosed with breast (BC) or colorectal (CRC) cancer from 2005 to 2014. Methods: Data included 1360 BC cases (median age 55.1 years) and 722 CRC cases (median age: 59.5 years; 52.5{\%} men) recorded by the Gaza Cancer Registry according to a standard protocol. Clinical information was available for cases diagnosed in 2005-2006 only. Survival probabilities were estimated by Kaplan-Meyer method, while hazard ratios (HRs) and 95{\%} confidence intervals (CI), adjusted for age and sex, were computed to assess factors associated with the risk of death. Results: Five-year survival was 65.1{\%} for women with BC and 50.2{\%} for patients with CRC. Advanced age (> 65 years), stage, and grade increased the death risk. Full access to therapies was associated with a reduced risk of death as compared with patients who had limited access (HR = 0.26, 95{\%} CI:0.13-0.51 for BC; and HR = 0.11, 95{\%} CI:0.04-0.31 for CRC). Conclusion(s): The 5-year survival after BC or CRC in the Gaza Strip was in line with estimates from surrounding Arab countries, but it was much lower than in developed Mediterranean countries (e.g., in Italy or in Jewish people in Israel).",
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AU - Pierannunzio, Daniela

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