Survival and prognostic factors of women with advanced ovarian cancer and complete response after a carboplatin-paclitaxel chemotherapy

Gianpiero Polverino, Fabio Parazzini, Giovanna Stellato, Giovanna Scarfone, Sonia Cipriani, Giorgio Bolis

Research output: Contribution to journalArticle

Abstract

Objective. We evaluated the characteristics and determinants of 5-year survival in ovarian cancer patients with complete response after first line treatment who entered a randomised study comparing two different chemotherapeutic schedules. Methods. This analysis included 232 ovarian cancer patients with complete response after first line surgery and chemotherapy coming from a large randomised trial comparing the effect of different doses of paclitaxel combined with fixed doses of carboplatin. Results. The 5-year overall survival in patients was 57.3%. The difference in 5-year survival for age 1 cm: these differences were statistically significant (P <0.006). Conclusion. This study shows that in women with ovarian cancer and complete response after first line surgery and chemotherapy, age, histotype and residual tumour after surgery are determinants of 5-year overall survival.

Original languageEnglish
Pages (from-to)343-347
Number of pages5
JournalGynecologic Oncology
Volume99
Issue number2
DOIs
Publication statusPublished - Nov 2005

Keywords

  • Ovarian cancer
  • Prognostic factors
  • Survivals complete responses

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

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