Survival in high-grade osteosarcoma: Improvement over 21 years at a single institution

P. Picci, M. Mercuri, S. Ferrari, M. Alberghini, A. Briccoli, C. Ferrari, E. Pignotti, G. Bacci

Research output: Contribution to journalArticle

Abstract

Background: The purpose of this study was to analyze improvements in overall survival over 21 years (1982-2002), with a 5-year minimum follow-up, in the largest series from a single center ever reported. Materials and methods: All diagnoses of high-grade osteosarcoma were included despite histological varieties, age, site and stage. Of the 1656 cases observed, 198 patients were excluded (41 consultation only, 129 low-grade varieties, and 28 lost to follow-up). Within 1458 included patients, 1032 had characteristics to be enrolled in conventional clinical trials (classic histology, age

Original languageEnglish
Pages (from-to)1366-1373
Number of pages8
JournalAnnals of Oncology
Volume21
Issue number6
DOIs
Publication statusPublished - Nov 4 2009

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Keywords

  • Bone neoplasms
  • Osteosarcoma
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Medicine(all)

Cite this

Picci, P., Mercuri, M., Ferrari, S., Alberghini, M., Briccoli, A., Ferrari, C., Pignotti, E., & Bacci, G. (2009). Survival in high-grade osteosarcoma: Improvement over 21 years at a single institution. Annals of Oncology, 21(6), 1366-1373. https://doi.org/10.1093/annonc/mdp502