Survival of 793 patients with amyotrophic lateral sclerosis diagnosed over a 28-year period

Daniela Testa, Roberta Lovati, Massimo Ferrarini, Fabrizio Salmoiraghi, Graziella Filippini

Research output: Contribution to journalArticlepeer-review

Abstract

We reviewed retrospectively 793 consecutive patients discharged with ALS diagnosis between 1971 and 1998 to identify survival predictors. Vital status in July 2001 was known for all patients. Mean age at onset was 56 (SD 11.7) years and mean age at diagnosis was 57.4 (SD 11.5) years. Onset symptoms were bulbar in 20.8% of patients. The median survival time from symptoms onset was 2.9 years (95% CI 2.7-3.1). Survival from onset was 93% after one, 48% after three and 24% after five years. Median survival was shorter in patients with time between onset and diagnosis 23 months; (2.1 years vs. 5.9 years; P

Original languageEnglish
Pages (from-to)208-212
Number of pages5
JournalAmyotrophic Lateral Sclerosis and Other Motor Neuron Disorders
Volume5
Issue number4
DOIs
Publication statusPublished - Dec 2004

Keywords

  • Amyotrophic lateral sclerosis
  • Epidemiology
  • Mortality
  • Survival predictors

ASJC Scopus subject areas

  • Clinical Neurology

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