Survival of 86,690 patients with thyroid cancer: A population-based study in 29 European countries from EUROCARE-5.

L Dal Maso, A Tavilla, F Pacini, D Serraino, B A C van Dijk, M D Chirlaque, R Capocaccia, N Larrañaga, M Colonna, D Agius, E Ardanaz, J Rubió-Casadevall, A Kowalska, S Virdone, S Mallone, H Amash, R De Angelis, EUROCARE-5 Working Group, Lucia Mangone, Massimo Vicentini

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Incidence rates of thyroid cancer (TC) increased in several countries during the last 30 years, while mortality rates remained unchanged, raising important questions for treatment and follow-up of TC patients. This study updates population-based estimates of relative survival (RS) after TC diagnosis in Europe by sex, country, age, period and histology.METHODS: Data from 87 cancer registries in 29 countries were extracted from the EUROCARE-5 dataset. One- and 5-year RS were estimated using the cohort approach for 86,690 adult TC patients diagnosed in 2000-2007 and followed-up to 12/31/2008. RS trends in 1999-2007 and 10-year RS in 2005-2007 were estimated using the period approach.RESULTS: In Europe 2000-2007, 5-year RS after TC was 88% in women and 81% in men. Survival rates varied by country and were strongly correlated (Pearson ρ = 75%) with country-specific incidence rates. Five-year RS decreased with age (in women from >95% at age 15-54 to 57% at age 75+), from 98% in women and 94% in men with papillary TC to 14% in women and 12% in men with anaplastic TC. Proportion of papillary TC varied by country and increased over time, while survival rates were similar across areas and periods. In 1999-2007, 5-year RS increased by five percentage points for all TCs but only by two for papillary and by four for follicular TC. Ten-year RS in 2005-2007 was 89% in women and 79% in men.CONCLUSIONS: The reported increasing TC survival trend and differences by area are mainly explained by the varying histological case-mix of cases.
Original languageEnglish
Pages (from-to)140-152
Number of pages13
JournalEuropean Journal of Cancer
Volume77
DOIs
Publication statusPublished - May 2017

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Thyroid Neoplasms
Survival
Population
Survival Rate
Diagnosis-Related Groups
Incidence
Registries
Histology
Mortality

Keywords

  • Adenocarcinoma, Follicular
  • Adolescent
  • Adult
  • Aged
  • Carcinoma
  • Carcinoma, Papillary
  • Diagnosis-Related Groups
  • Europe
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Registries
  • Residence Characteristics
  • Sex Distribution
  • Thyroid Neoplasms
  • Young Adult
  • Journal Article
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

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Survival of 86,690 patients with thyroid cancer : A population-based study in 29 European countries from EUROCARE-5. / Dal Maso, L; Tavilla, A; Pacini, F; Serraino, D; van Dijk, B A C; Chirlaque, M D; Capocaccia, R; Larrañaga, N; Colonna, M; Agius, D; Ardanaz, E; Rubió-Casadevall, J; Kowalska, A; Virdone, S; Mallone, S; Amash, H; De Angelis, R; Group, EUROCARE-5 Working; Mangone, Lucia; Vicentini, Massimo.

In: European Journal of Cancer, Vol. 77, 05.2017, p. 140-152.

Research output: Contribution to journalArticle

Dal Maso, L, Tavilla, A, Pacini, F, Serraino, D, van Dijk, BAC, Chirlaque, MD, Capocaccia, R, Larrañaga, N, Colonna, M, Agius, D, Ardanaz, E, Rubió-Casadevall, J, Kowalska, A, Virdone, S, Mallone, S, Amash, H, De Angelis, R, Group, EUROCAREW, Mangone, L & Vicentini, M 2017, 'Survival of 86,690 patients with thyroid cancer: A population-based study in 29 European countries from EUROCARE-5.', European Journal of Cancer, vol. 77, pp. 140-152. https://doi.org/10.1016/j.ejca.2017.02.023
Dal Maso, L ; Tavilla, A ; Pacini, F ; Serraino, D ; van Dijk, B A C ; Chirlaque, M D ; Capocaccia, R ; Larrañaga, N ; Colonna, M ; Agius, D ; Ardanaz, E ; Rubió-Casadevall, J ; Kowalska, A ; Virdone, S ; Mallone, S ; Amash, H ; De Angelis, R ; Group, EUROCARE-5 Working ; Mangone, Lucia ; Vicentini, Massimo. / Survival of 86,690 patients with thyroid cancer : A population-based study in 29 European countries from EUROCARE-5. In: European Journal of Cancer. 2017 ; Vol. 77. pp. 140-152.
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title = "Survival of 86,690 patients with thyroid cancer: A population-based study in 29 European countries from EUROCARE-5.",
abstract = "BACKGROUND: Incidence rates of thyroid cancer (TC) increased in several countries during the last 30 years, while mortality rates remained unchanged, raising important questions for treatment and follow-up of TC patients. This study updates population-based estimates of relative survival (RS) after TC diagnosis in Europe by sex, country, age, period and histology.METHODS: Data from 87 cancer registries in 29 countries were extracted from the EUROCARE-5 dataset. One- and 5-year RS were estimated using the cohort approach for 86,690 adult TC patients diagnosed in 2000-2007 and followed-up to 12/31/2008. RS trends in 1999-2007 and 10-year RS in 2005-2007 were estimated using the period approach.RESULTS: In Europe 2000-2007, 5-year RS after TC was 88{\%} in women and 81{\%} in men. Survival rates varied by country and were strongly correlated (Pearson ρ = 75{\%}) with country-specific incidence rates. Five-year RS decreased with age (in women from >95{\%} at age 15-54 to 57{\%} at age 75+), from 98{\%} in women and 94{\%} in men with papillary TC to 14{\%} in women and 12{\%} in men with anaplastic TC. Proportion of papillary TC varied by country and increased over time, while survival rates were similar across areas and periods. In 1999-2007, 5-year RS increased by five percentage points for all TCs but only by two for papillary and by four for follicular TC. Ten-year RS in 2005-2007 was 89{\%} in women and 79{\%} in men.CONCLUSIONS: The reported increasing TC survival trend and differences by area are mainly explained by the varying histological case-mix of cases.",
keywords = "Adenocarcinoma, Follicular, Adolescent, Adult, Aged, Carcinoma, Carcinoma, Papillary, Diagnosis-Related Groups, Europe, Female, Humans, Incidence, Male, Middle Aged, Registries, Residence Characteristics, Sex Distribution, Thyroid Neoplasms, Young Adult, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't",
author = "{Dal Maso}, L and A Tavilla and F Pacini and D Serraino and {van Dijk}, {B A C} and Chirlaque, {M D} and R Capocaccia and N Larra{\~n}aga and M Colonna and D Agius and E Ardanaz and J Rubi{\'o}-Casadevall and A Kowalska and S Virdone and S Mallone and H Amash and {De Angelis}, R and Group, {EUROCARE-5 Working} and Lucia Mangone and Massimo Vicentini",
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year = "2017",
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doi = "10.1016/j.ejca.2017.02.023",
language = "English",
volume = "77",
pages = "140--152",
journal = "European Journal of Cancer",
issn = "0959-8049",
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TY - JOUR

T1 - Survival of 86,690 patients with thyroid cancer

T2 - A population-based study in 29 European countries from EUROCARE-5.

AU - Dal Maso, L

AU - Tavilla, A

AU - Pacini, F

AU - Serraino, D

AU - van Dijk, B A C

AU - Chirlaque, M D

AU - Capocaccia, R

AU - Larrañaga, N

AU - Colonna, M

AU - Agius, D

AU - Ardanaz, E

AU - Rubió-Casadevall, J

AU - Kowalska, A

AU - Virdone, S

AU - Mallone, S

AU - Amash, H

AU - De Angelis, R

AU - Group, EUROCARE-5 Working

AU - Mangone, Lucia

AU - Vicentini, Massimo

N1 - Copyright © 2017 Elsevier Ltd. All rights reserved.

PY - 2017/5

Y1 - 2017/5

N2 - BACKGROUND: Incidence rates of thyroid cancer (TC) increased in several countries during the last 30 years, while mortality rates remained unchanged, raising important questions for treatment and follow-up of TC patients. This study updates population-based estimates of relative survival (RS) after TC diagnosis in Europe by sex, country, age, period and histology.METHODS: Data from 87 cancer registries in 29 countries were extracted from the EUROCARE-5 dataset. One- and 5-year RS were estimated using the cohort approach for 86,690 adult TC patients diagnosed in 2000-2007 and followed-up to 12/31/2008. RS trends in 1999-2007 and 10-year RS in 2005-2007 were estimated using the period approach.RESULTS: In Europe 2000-2007, 5-year RS after TC was 88% in women and 81% in men. Survival rates varied by country and were strongly correlated (Pearson ρ = 75%) with country-specific incidence rates. Five-year RS decreased with age (in women from >95% at age 15-54 to 57% at age 75+), from 98% in women and 94% in men with papillary TC to 14% in women and 12% in men with anaplastic TC. Proportion of papillary TC varied by country and increased over time, while survival rates were similar across areas and periods. In 1999-2007, 5-year RS increased by five percentage points for all TCs but only by two for papillary and by four for follicular TC. Ten-year RS in 2005-2007 was 89% in women and 79% in men.CONCLUSIONS: The reported increasing TC survival trend and differences by area are mainly explained by the varying histological case-mix of cases.

AB - BACKGROUND: Incidence rates of thyroid cancer (TC) increased in several countries during the last 30 years, while mortality rates remained unchanged, raising important questions for treatment and follow-up of TC patients. This study updates population-based estimates of relative survival (RS) after TC diagnosis in Europe by sex, country, age, period and histology.METHODS: Data from 87 cancer registries in 29 countries were extracted from the EUROCARE-5 dataset. One- and 5-year RS were estimated using the cohort approach for 86,690 adult TC patients diagnosed in 2000-2007 and followed-up to 12/31/2008. RS trends in 1999-2007 and 10-year RS in 2005-2007 were estimated using the period approach.RESULTS: In Europe 2000-2007, 5-year RS after TC was 88% in women and 81% in men. Survival rates varied by country and were strongly correlated (Pearson ρ = 75%) with country-specific incidence rates. Five-year RS decreased with age (in women from >95% at age 15-54 to 57% at age 75+), from 98% in women and 94% in men with papillary TC to 14% in women and 12% in men with anaplastic TC. Proportion of papillary TC varied by country and increased over time, while survival rates were similar across areas and periods. In 1999-2007, 5-year RS increased by five percentage points for all TCs but only by two for papillary and by four for follicular TC. Ten-year RS in 2005-2007 was 89% in women and 79% in men.CONCLUSIONS: The reported increasing TC survival trend and differences by area are mainly explained by the varying histological case-mix of cases.

KW - Adenocarcinoma, Follicular

KW - Adolescent

KW - Adult

KW - Aged

KW - Carcinoma

KW - Carcinoma, Papillary

KW - Diagnosis-Related Groups

KW - Europe

KW - Female

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Registries

KW - Residence Characteristics

KW - Sex Distribution

KW - Thyroid Neoplasms

KW - Young Adult

KW - Journal Article

KW - Multicenter Study

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.ejca.2017.02.023

DO - 10.1016/j.ejca.2017.02.023

M3 - Article

VL - 77

SP - 140

EP - 152

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

ER -