Susceptibility of human lymphoblastoid B-cell line CE to HIV1 infection

M. B. Valli, G. Carloni, L. Bertolini

Research output: Contribution to journalArticle

Abstract

In this preliminary report, we provide evidence that the human B- lymphoblastoid cell line (LCL) CE, bone-marrow-derived, previously reported to be permissive to hepatitis C virus, is also permissive to HIV1 infection. HIV1 genomes were detectable in cell supernatants, virus RNA transcripts and proviral DNAs in cell extracts at different times postinfection. Therefore, we propose this LCL cell line as a tool for exploring the mutual interactions of the two viruses in double-infected cells.

Original languageEnglish
Pages (from-to)307-309
Number of pages3
JournalResearch in Virology
Volume149
Issue number5
DOIs
Publication statusPublished - Sep 1998

Fingerprint

B-Lymphocytes
Cell Line
Infection
RNA Viruses
Cell Extracts
Hepacivirus
Bone Marrow
Genome
Viruses
DNA

Keywords

  • B lymphocyte
  • CE cell line
  • HIV1
  • PCR

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Susceptibility of human lymphoblastoid B-cell line CE to HIV1 infection. / Valli, M. B.; Carloni, G.; Bertolini, L.

In: Research in Virology, Vol. 149, No. 5, 09.1998, p. 307-309.

Research output: Contribution to journalArticle

Valli, M. B. ; Carloni, G. ; Bertolini, L. / Susceptibility of human lymphoblastoid B-cell line CE to HIV1 infection. In: Research in Virology. 1998 ; Vol. 149, No. 5. pp. 307-309.
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