Susceptibility of streptococcus pneumoniae strains isolated in Italy to penicillin and ten other antibiotics

Anna Marchese, Eugenio A. Debbia, Andrea Arvigo, Adelaide Pesce, Gian Carlo Schito

Research output: Contribution to journalArticlepeer-review

Abstract

The susceptibility of 312 Streptococcus pneumoniae strains isolated during 1993 in Italy has been studied. Overall resistance to penicillin, erythromycin and co-trimoxazole was 5.5, 6 and 18% respectively. The penicillin resistant isolates (nine displaying low- and eight high-level resistance) were further tested against cefotaxime, ceftriaxone, cefepime, cefodizime, ceftazidime, imipenem, meropenem and rifampicin. The low-level penicillin resistant strains were inhibited by all these drugs. Among the eight high-level penicillin resistant pneumococci, four were resistant to one or more cephalosporins. Imipenem and rifampicin remained effective against all isolates. In comparison with other European Mediterranean countries, penicillin resistance is a minor threat at present in Italy.

Original languageEnglish
Pages (from-to)833-837
Number of pages5
JournalJournal of Antimicrobial Chemotherapy
Volume36
Issue number5
DOIs
Publication statusPublished - Nov 1995

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)
  • Pharmacology

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