Susceptibility of streptococcus pneumoniae strains isolated in Italy to penicillin and ten other antibiotics

Anna Marchese; Eugenio A. Debbia; Andrea Arvigo; Adelaide Pesce; Gian Carlo Schito

doi:10.1093/jac/36.5.833

Susceptibility of streptococcus pneumoniae strains isolated in Italy to penicillin and ten other antibiotics

Anna Marchese, Eugenio A. Debbia, Andrea Arvigo, Adelaide Pesce, Gian Carlo Schito

A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)

Research output: Contribution to journal › Article › peer-review

Abstract

The susceptibility of 312 Streptococcus pneumoniae strains isolated during 1993 in Italy has been studied. Overall resistance to penicillin, erythromycin and co-trimoxazole was 5.5, 6 and 18% respectively. The penicillin resistant isolates (nine displaying low- and eight high-level resistance) were further tested against cefotaxime, ceftriaxone, cefepime, cefodizime, ceftazidime, imipenem, meropenem and rifampicin. The low-level penicillin resistant strains were inhibited by all these drugs. Among the eight high-level penicillin resistant pneumococci, four were resistant to one or more cephalosporins. Imipenem and rifampicin remained effective against all isolates. In comparison with other European Mediterranean countries, penicillin resistance is a minor threat at present in Italy.

Original language	English
Pages (from-to)	833-837
Number of pages	5
Journal	Journal of Antimicrobial Chemotherapy
Volume	36
Issue number	5
DOIs	https://doi.org/10.1093/jac/36.5.833
Publication status	Published - Nov 1995

ASJC Scopus subject areas

Statistics, Probability and Uncertainty
Applied Mathematics
Physiology (medical)
Infectious Diseases
Pharmacology (medical)
Pharmacology

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title = "Susceptibility of streptococcus pneumoniae strains isolated in Italy to penicillin and ten other antibiotics",

abstract = "The susceptibility of 312 Streptococcus pneumoniae strains isolated during 1993 in Italy has been studied. Overall resistance to penicillin, erythromycin and co-trimoxazole was 5.5, 6 and 18% respectively. The penicillin resistant isolates (nine displaying low- and eight high-level resistance) were further tested against cefotaxime, ceftriaxone, cefepime, cefodizime, ceftazidime, imipenem, meropenem and rifampicin. The low-level penicillin resistant strains were inhibited by all these drugs. Among the eight high-level penicillin resistant pneumococci, four were resistant to one or more cephalosporins. Imipenem and rifampicin remained effective against all isolates. In comparison with other European Mediterranean countries, penicillin resistance is a minor threat at present in Italy.",

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AU - Schito, Gian Carlo

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