Susceptibility to allergy in adoptive children: a cross-sectional study at "Bambino Gesù Children's Hospital"

Hyppolite K Tchidjou, Maria Fenicia Vescio, Jessica Serafinelli, Rosaria Giampaolo, Alessandro Jenkner, Mathurin C Tadonkeng, Luca Avellis, Alessandro Fiocchi, Patrizio Pezzotti, Giovanni Rezza, Paolo Rossi

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Prevalence of allergy has steeply increased during the past few decades, particularly in high-income countries. The development of atopy could present different characteristics in internationally adopted children with regard to incidence, specific patterns of allergies and timing of occurrence. We aimed to investigate the occurrence of allergic diseases among adopted children in Italy.

METHODS: We collected demographic information, preadoption immunization data, infectious diseases screening results, immunological status, and performed hematological and biochemical tests according to a standardized protocol in 108 adopted children.

RESULTS: At initial visit (mean age was 5.7 ± 3.2 years), 48 children displayed elevated total serum IgE levels with a prevalence of 56.5% (95%CI: 0.45; 0.67). The prevalences of children screened positive for one or more food allergens and inhalants were 30.1% (95%CI: 19.9%; 42.0%) and 34.3% (95%CI: 23.3%; 46.6%) respectively, only 9 children exhibited abnormal absolute eosinophil counts, 23 (21.3%) had a parasitic infection and 60 (55.6%) had received at least one dose of vaccine.

CONCLUSIONS: Children without medical records or with a past medical history suggestive of atopy should perform a thorough allergy evaluation at the time of adoption. Our study offers also a glimpse at the vaccination status and immune-allergic profiles of recent migrant children in Italy.

Original languageEnglish
Pages (from-to)3
Number of pages9
JournalItalian Journal of Pediatrics
Volume44
Issue number1
DOIs
Publication statusPublished - Jan 4 2018

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Hypersensitivity
Cross-Sectional Studies
Italy
Parasitic Diseases
Hematologic Tests
Eosinophils
Allergens
Immunoglobulin E
Medical Records
Communicable Diseases
Immunization
Vaccination
Vaccines
Demography
Food
Incidence
Serum

Keywords

  • Child
  • Child, Adopted/statistics & numerical data
  • Child, Preschool
  • Cross-Sectional Studies
  • Disease Susceptibility/epidemiology
  • Emigration and Immigration/statistics & numerical data
  • Female
  • Hospitals, Pediatric
  • Humans
  • Hypersensitivity/diagnosis
  • Infant
  • Italy/epidemiology
  • Male
  • Mass Screening/methods
  • Prevalence
  • Reference Values
  • Risk Assessment

Cite this

@article{4219fe8eae71499c88eff9190afacd72,
title = "Susceptibility to allergy in adoptive children: a cross-sectional study at {"}Bambino Ges{\`u} Children's Hospital{"}",
abstract = "BACKGROUND: Prevalence of allergy has steeply increased during the past few decades, particularly in high-income countries. The development of atopy could present different characteristics in internationally adopted children with regard to incidence, specific patterns of allergies and timing of occurrence. We aimed to investigate the occurrence of allergic diseases among adopted children in Italy.METHODS: We collected demographic information, preadoption immunization data, infectious diseases screening results, immunological status, and performed hematological and biochemical tests according to a standardized protocol in 108 adopted children.RESULTS: At initial visit (mean age was 5.7 ± 3.2 years), 48 children displayed elevated total serum IgE levels with a prevalence of 56.5{\%} (95{\%}CI: 0.45; 0.67). The prevalences of children screened positive for one or more food allergens and inhalants were 30.1{\%} (95{\%}CI: 19.9{\%}; 42.0{\%}) and 34.3{\%} (95{\%}CI: 23.3{\%}; 46.6{\%}) respectively, only 9 children exhibited abnormal absolute eosinophil counts, 23 (21.3{\%}) had a parasitic infection and 60 (55.6{\%}) had received at least one dose of vaccine.CONCLUSIONS: Children without medical records or with a past medical history suggestive of atopy should perform a thorough allergy evaluation at the time of adoption. Our study offers also a glimpse at the vaccination status and immune-allergic profiles of recent migrant children in Italy.",
keywords = "Child, Child, Adopted/statistics & numerical data, Child, Preschool, Cross-Sectional Studies, Disease Susceptibility/epidemiology, Emigration and Immigration/statistics & numerical data, Female, Hospitals, Pediatric, Humans, Hypersensitivity/diagnosis, Infant, Italy/epidemiology, Male, Mass Screening/methods, Prevalence, Reference Values, Risk Assessment",
author = "Tchidjou, {Hyppolite K} and Vescio, {Maria Fenicia} and Jessica Serafinelli and Rosaria Giampaolo and Alessandro Jenkner and Tadonkeng, {Mathurin C} and Luca Avellis and Alessandro Fiocchi and Patrizio Pezzotti and Giovanni Rezza and Paolo Rossi",
year = "2018",
month = "1",
day = "4",
doi = "10.1186/s13052-017-0440-2",
language = "English",
volume = "44",
pages = "3",
journal = "Italian Journal of Pediatrics",
issn = "1720-8424",
publisher = "BioMed Central Ltd.",
number = "1",

}

TY - JOUR

T1 - Susceptibility to allergy in adoptive children

T2 - a cross-sectional study at "Bambino Gesù Children's Hospital"

AU - Tchidjou, Hyppolite K

AU - Vescio, Maria Fenicia

AU - Serafinelli, Jessica

AU - Giampaolo, Rosaria

AU - Jenkner, Alessandro

AU - Tadonkeng, Mathurin C

AU - Avellis, Luca

AU - Fiocchi, Alessandro

AU - Pezzotti, Patrizio

AU - Rezza, Giovanni

AU - Rossi, Paolo

PY - 2018/1/4

Y1 - 2018/1/4

N2 - BACKGROUND: Prevalence of allergy has steeply increased during the past few decades, particularly in high-income countries. The development of atopy could present different characteristics in internationally adopted children with regard to incidence, specific patterns of allergies and timing of occurrence. We aimed to investigate the occurrence of allergic diseases among adopted children in Italy.METHODS: We collected demographic information, preadoption immunization data, infectious diseases screening results, immunological status, and performed hematological and biochemical tests according to a standardized protocol in 108 adopted children.RESULTS: At initial visit (mean age was 5.7 ± 3.2 years), 48 children displayed elevated total serum IgE levels with a prevalence of 56.5% (95%CI: 0.45; 0.67). The prevalences of children screened positive for one or more food allergens and inhalants were 30.1% (95%CI: 19.9%; 42.0%) and 34.3% (95%CI: 23.3%; 46.6%) respectively, only 9 children exhibited abnormal absolute eosinophil counts, 23 (21.3%) had a parasitic infection and 60 (55.6%) had received at least one dose of vaccine.CONCLUSIONS: Children without medical records or with a past medical history suggestive of atopy should perform a thorough allergy evaluation at the time of adoption. Our study offers also a glimpse at the vaccination status and immune-allergic profiles of recent migrant children in Italy.

AB - BACKGROUND: Prevalence of allergy has steeply increased during the past few decades, particularly in high-income countries. The development of atopy could present different characteristics in internationally adopted children with regard to incidence, specific patterns of allergies and timing of occurrence. We aimed to investigate the occurrence of allergic diseases among adopted children in Italy.METHODS: We collected demographic information, preadoption immunization data, infectious diseases screening results, immunological status, and performed hematological and biochemical tests according to a standardized protocol in 108 adopted children.RESULTS: At initial visit (mean age was 5.7 ± 3.2 years), 48 children displayed elevated total serum IgE levels with a prevalence of 56.5% (95%CI: 0.45; 0.67). The prevalences of children screened positive for one or more food allergens and inhalants were 30.1% (95%CI: 19.9%; 42.0%) and 34.3% (95%CI: 23.3%; 46.6%) respectively, only 9 children exhibited abnormal absolute eosinophil counts, 23 (21.3%) had a parasitic infection and 60 (55.6%) had received at least one dose of vaccine.CONCLUSIONS: Children without medical records or with a past medical history suggestive of atopy should perform a thorough allergy evaluation at the time of adoption. Our study offers also a glimpse at the vaccination status and immune-allergic profiles of recent migrant children in Italy.

KW - Child

KW - Child, Adopted/statistics & numerical data

KW - Child, Preschool

KW - Cross-Sectional Studies

KW - Disease Susceptibility/epidemiology

KW - Emigration and Immigration/statistics & numerical data

KW - Female

KW - Hospitals, Pediatric

KW - Humans

KW - Hypersensitivity/diagnosis

KW - Infant

KW - Italy/epidemiology

KW - Male

KW - Mass Screening/methods

KW - Prevalence

KW - Reference Values

KW - Risk Assessment

U2 - 10.1186/s13052-017-0440-2

DO - 10.1186/s13052-017-0440-2

M3 - Article

C2 - 29301554

VL - 44

SP - 3

JO - Italian Journal of Pediatrics

JF - Italian Journal of Pediatrics

SN - 1720-8424

IS - 1

ER -