Abstract
Approximately 20 years after the Seveso accident, we designed a case-control study on 101 subjects who developed chloracne after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and 211 controls from the same area, to establish the dose-exposure relation and to identify dioxin susceptibility factors. Subjects with elevated plasma TCDD levels (>10 pg/g fat) showed an almost 4 times higher risk of developing chloracne. Chloracne risk was higher in subjects with high TCDD plasma levels, young people (≤8 years) and/or those with fair hair. The health status of chloracne cases twenty years after the accident was not different from that of control subjects.
Translated title of the contribution | Susceptibility to dioxin among individuals from Seveso suffering from cloracne |
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Original language | Italian |
Pages (from-to) | 27-29 |
Number of pages | 3 |
Journal | Giornale Italiano di Medicina del Lavoro ed Ergonomia |
Volume | 26 |
Issue number | 4 SUPPL. |
Publication status | Published - 2004 |
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Rehabilitation